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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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270 RNA-SM complexes found
Structure of complex 8t2z

8t2z

Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, and A-site tRNA, messenger RNA, POST

SM: 3HE

Structure of complex 8t30

8t30

Hypomethylated yeast 80S bound with cycloheximide, unmodified U2921, mid rotated

SM: 3HE

Structure of complex 8u5j

8u5j

Structure of Mango III variant aptamer bound to T01-07M-B

SM: W6F

Structure of complex 8vuo

8vuo

Crystal structure of SARS-CoV-2 nsp16/nsp10 in complex with Cap-1 RNA

SM: SAH SAH

Structure of complex 8xsx

8xsx

Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2

SM: T1C T1C T1C T1C T1C T1C T1C

Structure of complex 8xsy

8xsy

Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled)

SM: T1C T1C T1C T1C T1C T1C T1C T1C

Structure of complex 8xsz

8xsz

Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA

SM: T1C T1C T1C T1C T1C

Structure of complex 8y5r

8y5r

E.coli Transcription translation coupling complex in TTC-B state 5 (subclass 1) containing mRNA with 27-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and fusidic acid

SM: FUA

Structure of complex 8y5t

8y5t

E.coli Transcription translation coupling complex in TTC-B state 5 (subclass 3) containing mRNA with 27-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and fusidic acid

SM: FUA

Structure of complex 8yoo

8yoo

Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline

SM: T1C T1C T1C T1C T1C T1C

Structure of complex 9bh5

9bh5

High-resolution C. elegans 80S ribosome structure - class 1

SM: 3HE

Structure of complex 9cai

9cai

High-resolution C. elegans 80S ribosome structure - class 1

SM: 3HE

Structure of complex 9dpl

9dpl

Human LysRS bound to cellular modified tRNA-Lys3 and AIMP2

SM: AMP

Structure of complex 9e71

9e71

Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9e7f

9e7f

Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome in complex with Dri

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9f37

9f37

Replication-like initiation state of influenza polymerase with GTP and CTP at respectively the -1 and +1 positions (strain A/little yellow-shouldered bat/Guatemala/060/2010/H17N10)

SM: CTP GTP

Structure of complex 9fhl

9fhl

High-resolution cryo-EM structure of Saccharolobus solfataricus 30S ribosomal subunit bound to mRNA and initiator tRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fqz

9fqz

CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1

SM: 3HE ANM GDP HYG

Structure of complex 9fra

9fra

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9frk

9frk

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9frl

9frl

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fs6

9fs6

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fs8

9fs8

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aEF1A-like mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fsf

9fsf

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fy0

9fy0

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9g30

9g30

The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) shows strong density for the A site tRNA

SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET SPK

Structure of complex 9g6j

9g6j

The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) with strong density for the P-site tRNA

SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET SPK YMZ

Structure of complex 9gha

9gha

Fusidic acid-locked Escherichia coli 70S ribosome with Staphylococcus aureus EF-G and a tRNA in pe/E chimeric state (CHI)

SM: FUA

Structure of complex 9ghb

9ghb

Fusidic acid-locked Escherichia coli 70S ribosome with Staphylococcus aureus EF-G in post-translocational state (POST)

SM: FUA

Structure of complex 9ghc

9ghc

Pre-release fusidic acid-locked Escherichia coli 70S ribosome with Staphylococus aureus EF-G and FusB (FusB-EF-G-70S)

SM: FUA GDP

Structure of complex 9h6i

9h6i

Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs, mRNA, and thermospermine

SM: EPE TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER

Structure of complex 9hes

9hes

Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs, mRNA, and thermospermine

SM: EPE TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER

Structure of complex 9hrd

9hrd

Crystal structure of the Class V GTP aptamer in complex with GTP

SM: GTP GTP GTP GTP

Structure of complex 9hrg

9hrg

Crystal structure of the Class V (G61A) GTP aptamer variant in complex with GTP

SM: GTP GTP GTP GTP

Structure of complex 9i9w

9i9w

Crystal structure containing UGGAA/UGGAA motif interacting with NCD molecule

SM: B2R B2R B2R

Structure of complex 9if0

9if0

RNA duplex containing UGGAA/UGGAA motif interacting with NCD molecule

SM: B2R B2R

Structure of complex 9l8f

9l8f

Crystal structure of RhoBAST aptamer in complex with TMR

SM: A1EI4

Structure of complex 9ljr

9ljr

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: CDP FAD

Structure of complex 9ljs

9ljs

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: CDP FAD

Structure of complex 9ljt

9ljt

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: CDP FAD

Structure of complex 9lju

9lju

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: FAD GDP

Structure of complex 9ljv

9ljv

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: C5P FAD

Structure of complex 9p6z

9p6z

In situ human P-Z state 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p72

9p72

In situ human P-E state 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p73

9p73

In situ human eEF2-A/P-P/E state 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p76

9p76

In situ human eEF1A-A/T-P state 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p78

9p78

In situ human Hibernating rotate 3 with E-site tRNA state 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p79

9p79

In situ human Hibernating rotate3 with Z site tRNA state 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7a

9p7a

In situ human hibernating class2 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7c

9p7c

In situ human Hibernating class3 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7d

9p7d

In situ human Hibernating class4 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7e

9p7e

In situ human Hibernating class5 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7f

9p7f

In situ HHT and CHX treated A-P state 80S ribosome

SM: HMT SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7g

9p7g

In situ HHT and CHX treated A-P-Z state 80S ribosome

SM: HMT SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7h

9p7h

In situ HHT and CHX treated human eEF1A-A/T-P state 80S ribosome

SM: 3HE HMT SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7i

9p7i

In situ HHT and CHX treated human eEF1A-A/T-P-Z state 80S ribosome

SM: 3HE HMT SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7j

9p7j

In situ HHT and CHX treated human P state 80S ribosome

SM: 3HE HMT SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7k

9p7k

In situ human post eEF1A-A/T-P-E state 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7l

9p7l

In situ human Post-eEF1A-AT-P state 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9p7n

9p7n

In situ human Post-eEF1A-A/T-P-Z state 80S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM