HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8xsy

System information

Experimental technique Electron Microscopy
Experimental resolution 3.00
System mass 4007.70 kDa
Deposition year 2024
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 8xsy
Reference Li Xiang, Wang Mengjiao, Denk Timo, Buschauer Robert, Li Yi, Beckmann Roland, Cheng Jingdong. . Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline Nature Communications

Compound T1C
Residue . / 5311
Chain KK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 562.52 Å3
Hydrophobicity 0.355
Hydrophilicity 0.959
Buriedness 0.707
Don/acc character 1.790
SiteScore 1.172
D Score 1.051

Compound T1C
Residue . / 5312
Chain LK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 408.51 Å3
Hydrophobicity 0.070
Hydrophilicity 1.227
Buriedness 0.657
Don/acc character 1.390
SiteScore 0.631
D Score 0.886

Compound T1C
Residue . / 5313
Chain MK / L5
Non-redundant True
Interacting RNA chains C/L8, A/L5
Volume 445.90 Å3
Hydrophobicity 0.151
Hydrophilicity 1.373
Buriedness 0.684
Don/acc character 1.046
SiteScore 1.141
D Score 0.903

Compound T1C
Residue . / 5314
Chain NK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 462.36 Å3
Hydrophobicity 0.102
Hydrophilicity 1.616
Buriedness 0.701
Don/acc character 0.737
SiteScore 1.002
D Score 0.834

Compound T1C
Residue . / 5315
Chain OK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 385.53 Å3
Hydrophobicity 0.070
Hydrophilicity 1.239
Buriedness 0.674
Don/acc character 2.226
SiteScore 1.134
D Score 0.941

Compound T1C
Residue . / 5316
Chain PK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 345.74 Å3
Hydrophobicity 1.059
Hydrophilicity 0.772
Buriedness 0.687
Don/acc character 3.888
SiteScore 1.045
D Score 1.101

Compound T1C
Residue . / 5317
Chain QK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 75.80 Å3
Hydrophobicity 0.093
Hydrophilicity 0.881
Buriedness 0.574
Don/acc character 4.602
SiteScore 0.609
D Score 0.563

Compound T1C
Residue . / 101
Chain SM / CC
Non-redundant True
Interacting RNA chains GC/CC, A/L5
Volume 66.89 Å3
Hydrophobicity 0.376
Hydrophilicity 0.699
Buriedness 0.566
Don/acc character 1.487
SiteScore 0.611
D Score 0.582