Complex 9ghc
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.79 |
| System mass | 2299.85 kDa |
| Deposition year | 2024 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 9ghc |
| Reference | González-López Adrián, Ge Xueliang, Larsson Daniel S. D., Sihlbom Wallem Carina, Sanyal Suparna, Selmer Maria. 2025. Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis Nature Communications |
| Equivalence Class |
NR_all_83717.187
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | FUA |
| Residue | . / 703 |
| Chain | QE / W |
| Non-redundant | True |
| Interacting RNA chains | EA/a |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | EA/a: rRNA |
| RNA family global | rRNA |
| Volume | 331.00 Å3 |
| Hydrophobicity | 0.626 |
| Hydrophilicity | 0.964 |
| Buriedness | 0.739 |
| Don/acc character | 0.683 |
| SiteScore | 1.038 |
| D Score | 1.064 |
| Kd | — |
| Compound | GDP |
| Residue | . / 701 |
| Chain | OE / W |
| Non-redundant | True |
| Interacting RNA chains | EA/a |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | EA/a: rRNA |
| RNA family global | rRNA |
| Volume | 407.48 Å3 |
| Hydrophobicity | 0.104 |
| Hydrophilicity | 1.628 |
| Buriedness | 0.730 |
| Don/acc character | 0.467 |
| SiteScore | 1.021 |
| D Score | 0.847 |
| Kd | — |