HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Compound SPK

Identifiers

  • Canonical SMILES: 
    [NH3+]CCC[NH2+]CCCC[NH2+]CCC[NH3+]
  • IUPAC name: 
    N,N'-bis(3-ammoniopropyl)butane-1,4-diaminium
  • InChi: 
    InChI=1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2/p+4
  • InChiKey: 
    PFNFFQXMRSDOHW-UHFFFAOYSA-R

Chemistry rules

Lipinski's RO5 Veber Pfizer's 3/75

External links

446718

RNA-SM complexes

PDB code Deposition date Reference publication
5t83 Sept. 6, 2016 Reiss Caroline W., Xiong Yong, Strobel Scott A.. . Structural Basis for Ligand Binding to the Guanidine-I Riboswitch Structure
8ogj March 20, 2023 Kolosova Olga, Zgadzay Yury, Stetsenko Artem, Sukhinina Anastasia P., Atamas Anastasia, Validov Shamil, Rogachev Andrey, Usachev Konstantin, Jenner Lasse, Dmitriev Sergey E., Yusupova Gulnara, Guskov Albert, Yusupov Marat. . Mechanism of read-through enhancement by aminoglycosides and mefloquine Proceedings of the National Academy of Sciences
8q5i Aug. 9, 2023 Kolosova O., Zgadzay Y., Stetsenko A., Atamas A., Wu C., Sachs M. S., Jenner L., Guskov A., Yusupov M.. . Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy Biopolymers and Cell
9g1z July 10, 2024 Kolosova Olga, Zgadzay Yury, Stetsenko Artem, Sukhinina Anastasia P., Atamas Anastasia, Validov Shamil, Rogachev Andrey, Usachev Konstantin, Jenner Lasse, Dmitriev Sergey E., Yusupova Gulnara, Guskov Albert, Yusupov Marat. . Mechanism of read-through enhancement by aminoglycosides and mefloquine Proceedings of the National Academy of Sciences
9g30 July 11, 2024 Kolosova Olga, Zgadzay Yury, Stetsenko Artem, Sukhinina Anastasia P., Atamas Anastasia, Validov Shamil, Rogachev Andrey, Usachev Konstantin, Jenner Lasse, Dmitriev Sergey E., Yusupova Gulnara, Guskov Albert, Yusupov Marat. . Mechanism of read-through enhancement by aminoglycosides and mefloquine Proceedings of the National Academy of Sciences
9g6j July 18, 2024 Kolosova Olga, Zgadzay Yury, Stetsenko Artem, Sukhinina Anastasia P., Atamas Anastasia, Validov Shamil, Rogachev Andrey, Usachev Konstantin, Jenner Lasse, Dmitriev Sergey E., Yusupova Gulnara, Guskov Albert, Yusupov Marat. . Mechanism of read-through enhancement by aminoglycosides and mefloquine Proceedings of the National Academy of Sciences

Physicochemical filters

Descriptor Lipinski's RO5 Veber Pfizer's 3/75
Compliance
MW 206.37 g/mol
HBA not available
HBD not available
HBA + HBD
AlogP not available
TPSA not available
RB not available

Radar chart