HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8xsx

System information

Experimental technique Electron Microscopy
Experimental resolution 2.40
System mass 4076.45 kDa
Deposition year 2024
Molecule type RNA/Protein
# RNA entities 4
Organism Homo
RCSB PDB Entry 8xsx
Reference Li Xiang, Wang Mengjiao, Denk Timo, Buschauer Robert, Li Yi, Beckmann Roland, Cheng Jingdong. . Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline Nature Communications

Compound T1C
Residue . / 5312
Chain LK / L5
Non-redundant True
Interacting RNA chains A/L5, WA/S2
Volume 261.02 Å3
Hydrophobicity 0.007
Hydrophilicity 1.331
Buriedness 0.636
Don/acc character 1.633
SiteScore 0.793
D Score 0.676

Compound T1C
Residue . / 5313
Chain MK / L5
Non-redundant True
Interacting RNA chains A/L5, C/L8
Volume 330.65 Å3
Hydrophobicity 0.231
Hydrophilicity 1.086
Buriedness 0.692
Don/acc character 1.551
SiteScore 0.962
D Score 0.958

Compound T1C
Residue . / 5314
Chain NK / L5
Non-redundant False
Interacting RNA chains A/L5
Volume 507.64 Å3
Hydrophobicity 0.266
Hydrophilicity 1.455
Buriedness 0.713
Don/acc character 0.815
SiteScore 1.010
D Score 0.894