HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8xsx

System information

Experimental technique Electron Microscopy
Experimental resolution 2.40
System mass 4076.45 kDa
Deposition year 2024
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 8xsx
Reference Li Xiang, Wang Mengjiao, Denk Timo, Buschauer Robert, Li Yi, Beckmann Roland, Cheng Jingdong. . Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline Nature Communications

Compound T1C
Residue . / 5312
Chain LK / L5
Non-redundant True
Interacting RNA chains WA/S2, A/L5
Volume 281.95 Å3
Hydrophobicity 0.024
Hydrophilicity 1.403
Buriedness 0.632
Don/acc character 1.193
SiteScore 0.973
D Score 0.691

Compound T1C
Residue . / 5313
Chain MK / L5
Non-redundant True
Interacting RNA chains C/L8, A/L5
Volume 393.76 Å3
Hydrophobicity 0.121
Hydrophilicity 1.653
Buriedness 0.692
Don/acc character 0.706
SiteScore 1.146
D Score 0.816

Compound T1C
Residue . / 5314
Chain NK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 509.36 Å3
Hydrophobicity 0.142
Hydrophilicity 1.600
Buriedness 0.708
Don/acc character 0.472
SiteScore 1.007
D Score 0.844

Compound T1C
Residue . / 5315
Chain OK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 274.06 Å3
Hydrophobicity 0.010
Hydrophilicity 1.304
Buriedness 0.626
Don/acc character 2.217
SiteScore 0.952
D Score 0.890

Compound T1C
Residue . / 5316
Chain PK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 332.71 Å3
Hydrophobicity 0.633
Hydrophilicity 0.887
Buriedness 0.664
Don/acc character 1.860
SiteScore 1.007
D Score 1.049

Compound T1C
Residue . / 5317
Chain QK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 104.96 Å3
Hydrophobicity 0.023
Hydrophilicity 1.097
Buriedness 0.618
Don/acc character 3.582
SiteScore 0.594
D Score 0.502

Compound T1C
Residue . / 101
Chain WM / CC
Non-redundant True
Interacting RNA chains GC/CC, A/L5
Volume 66.20 Å3
Hydrophobicity 0.197
Hydrophilicity 0.856
Buriedness 0.572
Don/acc character 1.076
SiteScore 0.538
D Score 0.474