HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8yoo

System information

Experimental technique Electron Microscopy
Experimental resolution 2.00
System mass 3842.67 kDa
Deposition year 2024
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 8yoo
Reference Li Xiang, Wang Mengjiao, Denk Timo, Buschauer Robert, Li Yi, Beckmann Roland, Cheng Jingdong. . Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline Nature Communications

Compound T1C
Residue . / 5309
Chain DK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 299.10 Å3
Hydrophobicity 0.185
Hydrophilicity 1.347
Buriedness 0.675
Don/acc character 0.643
SiteScore 1.135
D Score 0.906

Compound T1C
Residue . / 5310
Chain EK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 355.35 Å3
Hydrophobicity 0.098
Hydrophilicity 1.602
Buriedness 0.684
Don/acc character 0.722
SiteScore 0.657
D Score 0.790

Compound T1C
Residue . / 5311
Chain FK / L5
Non-redundant True
Interacting RNA chains A/L5, C/L8
Volume 343.34 Å3
Hydrophobicity 0.112
Hydrophilicity 1.437
Buriedness 0.690
Don/acc character 0.773
SiteScore 1.059
D Score 0.776

Compound T1C
Residue . / 5312
Chain GK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 350.55 Å3
Hydrophobicity 0.119
Hydrophilicity 1.562
Buriedness 0.677
Don/acc character 0.777
SiteScore 0.986
D Score 0.837

Compound T1C
Residue . / 5313
Chain HK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -

Compound T1C
Residue . / 1930
Chain IM / S2
Non-redundant True
Interacting RNA chains VA/S2
Volume 275.09 Å3
Hydrophobicity 0.063
Hydrophilicity 1.171
Buriedness 0.708
Don/acc character 2.275
SiteScore 1.111
D Score 0.925