HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8xsz

System information

Experimental technique Electron Microscopy
Experimental resolution 3.20
System mass 3982.70 kDa
Deposition year 2024
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 8xsz
Reference Li Xiang, Wang Mengjiao, Denk Timo, Buschauer Robert, Li Yi, Beckmann Roland, Cheng Jingdong. . Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline Nature Communications

Compound T1C
Residue . / 5310
Chain JK / L5
Non-redundant True
Interacting RNA chains A/L5, C/L8
Volume 338.20 Å3
Hydrophobicity 0.069
Hydrophilicity 1.588
Buriedness 0.698
Don/acc character 0.678
SiteScore 1.108
D Score 0.788

Compound T1C
Residue . / 5311
Chain KK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 73.75 Å3
Hydrophobicity 0.217
Hydrophilicity 0.988
Buriedness 0.567
Don/acc character 1.505
SiteScore 0.888
D Score 0.722

Compound T1C
Residue . / 5312
Chain LK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 350.55 Å3
Hydrophobicity 0.063
Hydrophilicity 1.237
Buriedness 0.665
Don/acc character 2.146
SiteScore 1.128
D Score 0.936

Compound T1C
Residue . / 5313
Chain MK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 451.39 Å3
Hydrophobicity 0.338
Hydrophilicity 1.079
Buriedness 0.679
Don/acc character 2.344
SiteScore 0.987
D Score 0.996

Compound T1C
Residue . / 5314
Chain NK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 171.84 Å3
Hydrophobicity 0.044
Hydrophilicity 1.460
Buriedness 0.666
Don/acc character 2.784
SiteScore 0.818
D Score 0.658