HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Compound EPE

Identifiers

  • Canonical SMILES: 
    OCCN1CCN(CC1)CC[S](O)(=O)=O
  • IUPAC name: 
    2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
  • InChi: 
    InChI=1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
  • InChiKey: 
    JKMHFZQWWAIEOD-UHFFFAOYSA-N

Chemistry rules

Lipinski's RO5 Veber Pfizer's 3/75

External links

23830 CHEMBL1232545 DB16872

RNA-SM complexes

PDB code Deposition date Reference publication
4pjo May 12, 2014 Kondo Yasushi, Oubridge Chris, van Roon Anne-Marie M, Nagai Kiyoshi. . Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5′ splice site recognition eLife
7kkv Oct. 28, 2020 Yang Yang, Harris Kimberly A., Widner Danielle L., Breaker Ronald R.. . Structure of a bacterial OapB protein with its OLE RNA target gives insights into the architecture of the OLE ribonucleoprotein complex Proceedings of the National Academy of Sciences
4wfa Sept. 14, 2014 Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. . Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences
6t3r Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4far May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4faq May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4wce Sept. 4, 2014 Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. . Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences
4fb0 May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
8rul Jan. 31, 2024 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
6t3n Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4e8m March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8m March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4fax May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
3v71 Dec. 20, 2011
9hes Nov. 14, 2024 Ko Donghwi, Ruonala Raili, Faille Alexandre, Hellmann Eva, Help Hanna, Liu Huili, Nielsen Ronni, Haakonsson Anders, De Diego Nuria, Paatero Anja, Shcherbii Mariia V., Stefanowicz Karolina, Ćavar Zeljković Sanja, Drud Lundager Rasmussen Tine, Novak Ondrej, Bodi Zsuzsanna, Eswaran Gugan, Wybouw Brecht, Bourdon Matthieu, Urbez Cristina, Liu Xiaonan, Salokas Kari, Öhman Tiina, Waldie Tanya, Törönen Petri, el-Showk Sedeer, Balcerowicz Martin, Besnard Fabrice, Liu Xiaomin, Perkins Patrick, Mazzoni-Putman Serina, Vainonen Julia P., Sierla Maija, Frilander Mikko J., Mandrup Susanne, Vernoux Teva, Ljung Karin, Ferrando Alejandro, Blazquez Miguel A., Holm Liisa, Fray Rupert, Varjosalo Markku, Leyser Ottoline, Paavilainen Ville O., Mähönen Ari Pekka, Stepanova Anna, Alonso Jose, Heber Steffen, Malinowski Robert, Kirpekar Finn, Warren Alan J., Helariutta Ykä. . Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate Science
8oly March 30, 2023 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4e8q March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
6t3k Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4wfa Sept. 14, 2014 Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. . Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences
8ols March 30, 2023 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4fb0 May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
9h3g Oct. 16, 2024 Ko Donghwi, Ruonala Raili, Faille Alexandre, Hellmann Eva, Help Hanna, Liu Huili, Nielsen Ronni, Haakonsson Anders, De Diego Nuria, Paatero Anja, Shcherbii Mariia V., Stefanowicz Karolina, Ćavar Zeljković Sanja, Drud Lundager Rasmussen Tine, Novak Ondrej, Bodi Zsuzsanna, Eswaran Gugan, Wybouw Brecht, Bourdon Matthieu, Urbez Cristina, Liu Xiaonan, Salokas Kari, Öhman Tiina, Waldie Tanya, Törönen Petri, el-Showk Sedeer, Balcerowicz Martin, Besnard Fabrice, Liu Xiaomin, Perkins Patrick, Mazzoni-Putman Serina, Vainonen Julia P., Sierla Maija, Frilander Mikko J., Mandrup Susanne, Vernoux Teva, Ljung Karin, Ferrando Alejandro, Blazquez Miguel A., Holm Liisa, Fray Rupert, Varjosalo Markku, Leyser Ottoline, Paavilainen Ville O., Mähönen Ari Pekka, Stepanova Anna, Alonso Jose, Heber Steffen, Malinowski Robert, Kirpekar Finn, Warren Alan J., Helariutta Ykä. . Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate Science
6t3s Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4e8t March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8q March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8m March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
6t3n Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4wfa Sept. 14, 2014 Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. . Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences
7k9d Sept. 29, 2020 Yang Yang, Harris Kimberly A., Widner Danielle L., Breaker Ronald R.. . Structure of a bacterial OapB protein with its OLE RNA target gives insights into the architecture of the OLE ribonucleoprotein complex Proceedings of the National Academy of Sciences
4e8p March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
9gmo Aug. 29, 2024 Akers Jared, Bothe Adrian, Suh Hanna, Jung Carmen, Stolp Zachary, Ghosh Tanushree, Yan Liewei, Wang Yuming, Grismer Tarabryn, Reyes Andreas, Hu Tianyi, Xu Shouling, Ban Nenad, Kostova Kamena. . ZNF574 is a Quality Control Factor For Defective Ribosome Biogenesis Intermediates []
4wfb Sept. 14, 2014 Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. . Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences
4fb0 May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4fax May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8r March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4fax May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
8ruh Jan. 30, 2024 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4e8k March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
8olz March 30, 2023 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4pjo May 12, 2014 Kondo Yasushi, Oubridge Chris, van Roon Anne-Marie M, Nagai Kiyoshi. . Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5′ splice site recognition eLife
8run Jan. 31, 2024 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4far May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8n March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
9h6i Oct. 24, 2024 Ko Donghwi, Ruonala Raili, Faille Alexandre, Hellmann Eva, Help Hanna, Liu Huili, Nielsen Ronni, Haakonsson Anders, De Diego Nuria, Paatero Anja, Shcherbii Mariia V., Stefanowicz Karolina, Ćavar Zeljković Sanja, Drud Lundager Rasmussen Tine, Novak Ondrej, Bodi Zsuzsanna, Eswaran Gugan, Wybouw Brecht, Bourdon Matthieu, Urbez Cristina, Liu Xiaonan, Salokas Kari, Öhman Tiina, Waldie Tanya, Törönen Petri, el-Showk Sedeer, Balcerowicz Martin, Besnard Fabrice, Liu Xiaomin, Perkins Patrick, Mazzoni-Putman Serina, Vainonen Julia P., Sierla Maija, Frilander Mikko J., Mandrup Susanne, Vernoux Teva, Ljung Karin, Ferrando Alejandro, Blazquez Miguel A., Holm Liisa, Fray Rupert, Varjosalo Markku, Leyser Ottoline, Paavilainen Ville O., Mähönen Ari Pekka, Stepanova Anna, Alonso Jose, Heber Steffen, Malinowski Robert, Kirpekar Finn, Warren Alan J., Helariutta Ykä. . Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate Science
4e8p March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8q March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8k March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8v March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4wfa Sept. 14, 2014 Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. . Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences
8a3d June 8, 2022 Faille Alexandre, Dent Kyle C., Pellegrino Simone, Jaako Pekka, Warren Alan J. . The chemical landscape of the human ribosome at 1.67 Å resolution []
6t3n Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4fb0 May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8t March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8k March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
6t3s Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4fau May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
8as7 Aug. 18, 2022 Williams Harry M, Thorkelsson Sigurdur R, Vogel Dominik, Milewski Morlin, Busch Carola, Cusack Stephen, Grünewald Kay, Quemin Emmanuelle R J, Rosenthal Maria. . Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein Nucleic Acids Research
4e8r March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8n March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
8rul Jan. 31, 2024 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4e8k March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8p March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4faq May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
6t3k Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4wfb Sept. 14, 2014 Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. . Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences
4faq May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4wfb Sept. 14, 2014 Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. . Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences
4e8r March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
6t3r Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4wfb Sept. 14, 2014 Eyal Zohar, Matzov Donna, Krupkin Miri, Wekselman Itai, Paukner Susanne, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Yonath Ada. . Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus Proceedings of the National Academy of Sciences
4e8m March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
6t3s Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4e8t March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8v March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4fau May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8p March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8t March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8m March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
5hl7 Jan. 14, 2016 Eyal Zohar, Matzov Donna, Krupkin Miri, Paukner Susanne, Riedl Rosemarie, Rozenberg Haim, Zimmerman Ella, Bashan Anat, Yonath Ada. . A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism Scientific Reports
4fau May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
8run Jan. 31, 2024 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4faw May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
8olv March 30, 2023 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
8oly March 30, 2023 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
8ols March 30, 2023 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4far May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
8oly March 30, 2023 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4e8t March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
6t3k Oct. 11, 2019 Manigrasso Jacopo, Chillón Isabel, Genna Vito, Vidossich Pietro, Somarowthu Srinivas, Pyle Anna Marie, De Vivo Marco, Marcia Marco. . Visualizing group II intron dynamics between the first and second steps of splicing Nature Communications
4faq May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
8olv March 30, 2023 Silvestri Ilaria, Manigrasso Jacopo, Andreani Alessandro, Brindani Nicoletta, Mas Caroline, Reiser Jean-Baptiste, Vidossich Pietro, Martino Gianfranco, McCarthy Andrew A., De Vivo Marco, Marcia Marco. . Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nature Communications
4e8k March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4faw May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8v March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4faq May 22, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
5nrg April 23, 2017 Matzov Donna, Eyal Zohar, Benhamou Raphael I., Shalev-Benami Moran, Halfon Yehuda, Krupkin Miri, Zimmerman Ella, Rozenberg Haim, Bashan Anat, Fridman Micha, Yonath Ada. . Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus Nucleic Acids Research
4e8v March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
4e8r March 20, 2012 Marcia Marco, Pyle Anna Marie. . Visualizing Group II Intron Catalysis through the Stages of Splicing Cell
9hmw Dec. 9, 2024 Ko Donghwi, Ruonala Raili, Faille Alexandre, Hellmann Eva, Help Hanna, Liu Huili, Nielsen Ronni, Haakonsson Anders, De Diego Nuria, Paatero Anja, Shcherbii Mariia V., Stefanowicz Karolina, Ćavar Zeljković Sanja, Drud Lundager Rasmussen Tine, Novak Ondrej, Bodi Zsuzsanna, Eswaran Gugan, Wybouw Brecht, Bourdon Matthieu, Urbez Cristina, Liu Xiaonan, Salokas Kari, Öhman Tiina, Waldie Tanya, Törönen Petri, el-Showk Sedeer, Balcerowicz Martin, Besnard Fabrice, Liu Xiaomin, Perkins Patrick, Mazzoni-Putman Serina, Vainonen Julia P., Sierla Maija, Frilander Mikko J., Mandrup Susanne, Vernoux Teva, Ljung Karin, Ferrando Alejandro, Blazquez Miguel A., Holm Liisa, Fray Rupert, Varjosalo Markku, Leyser Ottoline, Paavilainen Ville O., Mähönen Ari Pekka, Stepanova Anna, Alonso Jose, Heber Steffen, Malinowski Robert, Kirpekar Finn, Warren Alan J., Helariutta Ykä. . Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate Science

Physicochemical filters

Descriptor Lipinski's RO5 Veber Pfizer's 3/75
Compliance
MW 238.31 g/mol
HBA not available
HBD not available
HBA + HBD
AlogP not available
TPSA not available
RB not available

Radar chart