HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9dpl

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 2.80
System mass 170.37 kDa
Deposition year 2024
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 9dpl
Reference Devarkar Swapnil C, Budding Christina R, Pathirage Chathuri, Kavoor Arundhati, Herbert Cassandra, Limbach Patrick A, Musier-Forsyth Karin, Xiong Yong. 2025. Structural basis for aminoacylation of cellular modified tRNALys3 by human lysyl-tRNA synthetase Nucleic Acids Research
Equivalence Class NR_all_77079.2
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound AMP
Residue . / 602
Chain G / A
Non-redundant True
Interacting RNA chains C/C
RNA environment detailled protein, other
RNA environment global RNA/Other
RNA family chains C/C: tRNA
RNA family global tRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd