Complex 8vuo
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.39 |
| System mass | 105.71 kDa |
| Deposition year | 2024 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Betacoronavirus |
| RCSB PDB Entry | 8vuo |
| Reference | Misra Anurag, Rahisuddin R., Parihar Manish, Arya Shailee, Viswanathan Thiruselvam, Jackson Nathaniel, Qi Shan, Chan Siu-Hong, Harris Reuben S., Martinez-Sobrido Luis, Gupta Yogesh K.. 2025. Structural insights into the assembly and regulation of 2′-O RNA methylation by SARS-CoV-2 nsp16/nsp10 Structure |
| Equivalence Class |
NR_all_76335.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SAH |
| Residue | . / 302 |
| Chain | H / A |
| Non-redundant | False |
| Interacting RNA chains | E/E |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | E/E: unknown |
| RNA family global | unknown |
| Volume | 365.64 Å3 |
| Hydrophobicity | 0.923 |
| Hydrophilicity | 1.098 |
| Buriedness | 0.756 |
| Don/acc character | 1.018 |
| SiteScore | 1.039 |
| D Score | 1.035 |
| Kd | — |
| Compound | SAH |
| Residue | . / 302 |
| Chain | U / C |
| Non-redundant | False |
| Interacting RNA chains | F/F |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | F/F: unknown |
| RNA family global | unknown |
| Volume | 273.37 Å3 |
| Hydrophobicity | 0.542 |
| Hydrophilicity | 1.244 |
| Buriedness | 0.821 |
| Don/acc character | 1.168 |
| SiteScore | 1.082 |
| D Score | 1.027 |
| Kd | — |