HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Compound C5P

Identifiers

  • Canonical SMILES: 
    NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@H]2O
  • IUPAC name: 
    5'-cytidylic acid
  • InChi: 
    InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
  • InChiKey: 
    IERHLVCPSMICTF-XVFCMESISA-N

Chemistry rules

Lipinski's RO5 Veber Pfizer's 3/75

External links

6131 CHEMBL307679 DB03403

RNA-SM complexes

PDB code Deposition date Reference publication
4m2z Aug. 5, 2013 Court Donald L., Gan Jianhua, Liang Yu-He, Shaw Gary X., Tropea Joseph E., Costantino Nina, Waugh David S., Ji Xinhua. . RNase III: Genetics and Function; Structure and Mechanism Annual Review of Genetics
4m2z Aug. 5, 2013 Court Donald L., Gan Jianhua, Liang Yu-He, Shaw Gary X., Tropea Joseph E., Costantino Nina, Waugh David S., Ji Xinhua. . RNase III: Genetics and Function; Structure and Mechanism Annual Review of Genetics
5a0v April 23, 2015 Pei Xue-Yuan, Bralley Patricia, Jones George H., Luisi Ben F.. . Linkage of catalysis and 5′ end recognition in ribonuclease RNase J Nucleic Acids Research
6u7y Sept. 3, 2019 Zhang Wen, Kim Seohyun Chris, Tam Chun Pong, Lelyveld Victor S, Bala Saikat, Chaput John C, Szostak Jack W. . Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization Nucleic Acids Research
6u7z Sept. 3, 2019 Zhang Wen, Kim Seohyun Chris, Tam Chun Pong, Lelyveld Victor S, Bala Saikat, Chaput John C, Szostak Jack W. . Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization Nucleic Acids Research
8gs2 Sept. 4, 2022 Kato Kazuki, Okazaki Sae, Schmitt-Ulms Cian, Jiang Kaiyi, Zhou Wenyuan, Ishikawa Junichiro, Isayama Yukari, Adachi Shungo, Nishizawa Tomohiro, Makarova Kira S., Koonin Eugene V., Abudayyeh Omar O., Gootenberg Jonathan S., Nishimasu Hiroshi. . RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease Science
9ljv Jan. 15, 2025 Wang De-Ping, Zhao Rong, Hu Wen-Shu, Li Hai-Ning, Cao Ji-Min, Zhou Xin, Xiang Ye. . Structural insights into polymerase-catalyzed FAD capping of hepatitis C virus RNA Nature Communications

Physicochemical filters

Descriptor Lipinski's RO5 Veber Pfizer's 3/75
Compliance
MW 323.20 g/mol
HBA not available
HBD not available
HBA + HBD
AlogP not available
TPSA not available
RB not available

Radar chart