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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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855 RNA-SM complexes found
Structure of complex 5iwa

5iwa

Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic

SM: 6EK

Structure of complex 5j5b

5j5b

Structure of the WT E coli ribosome bound to tetracycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 TAC TAC

Structure of complex 5j7l

5j7l

Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 TAC TAC TAC TAC

Structure of complex 5j88

5j88

Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4

Structure of complex 5j8a

5j8a

Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 T1C T1C

Structure of complex 5j8b

5j8b

Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome

SM: GCP

Structure of complex 5j91

5j91

Structure of the Wild-type 70S E coli ribosome bound to Tigecycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 T1C T1C

Structure of complex 5jc9

5jc9

Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4

Structure of complex 5jte

5jte

Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA

SM: ERY

Structure of complex 5ju8

5ju8

Cryo-EM structure of an ErmBL-stalled ribosome in complex with P-, and E-tRNA

SM: ERY

Structure of complex 5jup

5jup

Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit)

SM: GDP

Structure of complex 5juu

5juu

Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit)

SM: GDP

Structure of complex 5kal

5kal

Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP and UpU

SM: UTP UTP

Structure of complex 5lks

5lks

Structure-function insights reveal the human ribosome as a cancer target for antibiotics

SM: 3HE

Structure of complex 5lmv

5lmv

Structure of bacterial 30S-IF1-IF2-IF3-mRNA-tRNA translation pre-initiation complex(state-III)

SM: FME

Structure of complex 5lzd

5lzd

Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)

SM: GNP

Structure of complex 5lzs

5lzs

Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B

SM: GDP

Structure of complex 5lzw

5lzw

Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.

SM: GCP

Structure of complex 5m1j

5m1j

Nonstop ribosomal complex bound with Dom34 and Hbs1

SM: GNP

Structure of complex 5ndg

5ndg

Crystal structure of geneticin (G418) bound to the yeast 80S ribosome

SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET

Structure of complex 5ndj

5ndj

Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking)

SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ

Structure of complex 5ndk

5ndk

Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA

SM: 8UZ 8UZ 8UZ 8UZ

Structure of complex 5ndv

5ndv

Structure of complex 5ndw

5ndw

Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome

SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ

Structure of complex 5nrg

5nrg

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02

SM: 95H EPE

Structure of complex 5ns4

5ns4

Crystal structures of Cy3 cyanine fluorophores stacked onto the end of double-stranded RNA

SM: 96T

Structure of complex 5obm

5obm

Crystal structure of Gentamicin bound to the yeast 80S ribosome

SM: LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL

Structure of complex 5omw

5omw

Mutant T252A of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5on2

5on2

Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5on3

5on3

Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of leucine in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5onh

5onh

Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation

SM: LSS LSS

Structure of complex 5ot7

5ot7

Elongation factor G-ribosome complex captures in the absence of inhibitors.

SM: GDP

Structure of complex 5tbw

5tbw

Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome

SM: 7AL 7AL

Structure of complex 5uj2

5uj2

Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations and Delta8 neta hairpoin loop deletion in complex with GS-639476 (diphsohate version of GS-9813), Mn2+ and symmetrical primer template 5'-AUAAAUUU

SM: 8B4

Structure of complex 5umd

5umd

Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine

SM: YMZ YMZ

Structure of complex 5v8i

5v8i

Thermus thermophilus 70S ribosome lacking ribosomal protein uS17

SM: ARG ARG

Structure of complex 5vw1

5vw1

Crystal structure of SpyCas9-sgRNA-AcrIIA4 ternary complex

SM: PG4

Structure of complex 5w0o

5w0o

Structure of human TUT7 catalytic module (CM) in complex with dsRNA

SM: UTP UTP

Structure of complex 5wdt

5wdt

70S ribosome-EF-Tu H84A complex with GppNHp

SM: FME GNP PHE

Structure of complex 5we4

5we4

70S ribosome-EF-Tu wt complex with GppNHp

SM: FME GNP PHE

Structure of complex 5we6

5we6

70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA

SM: FME PHE

Structure of complex 5wf0

5wf0

70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)

SM: FME PHE

Structure of complex 5wfk

5wfk

70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3)

SM: FME PHE

Structure of complex 5wfs

5wfs

70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4)

SM: FME GTP PHE

Structure of complex 5wis

5wis

Crystal structure of the Thermus thermophilus 70S ribosome in complex with methymycin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution

SM: MT9 MT9

Structure of complex 5wit

5wit

Crystal structure of the Thermus thermophilus 70S ribosome in complex with pikromycin and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution

SM: AQJ AQJ

Structure of complex 5wwr

5wwr

Crystal structure of human NSun6/tRNA/SFG

SM: SFG SFG

Structure of complex 5wws

5wws

Crystal structure of human NSun6/tRNA/SAM

SM: SAM SAM

Structure of complex 5zc9

5zc9

Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex

SM: RCG

Structure of complex 5zq0

5zq0

Crystal structure of spRlmCD with U747loop RNA

SM: SAH

Structure of complex 6aax

6aax

Crystal structure of TFB1M and h45 with SAM in homo sapiens

SM: SAM

Structure of complex 6az1

6az1

Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin

SM: PAR PAR PAR PAR PAR

Structure of complex 6az3

6az3

Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin

SM: PAR PAR PAR PAR PAR PAR PAR PAR PAR

Structure of complex 6b4v

6b4v

Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome

SM: BLS BLS

Structure of complex 6bjy

6bjy

VSV Nucleocapsid with Polyamide Bound

SM: DV4

Structure of complex 6boh

6boh

Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome

SM: BLS BLS

Structure of complex 6cao

6cao

Structure of the ribosomal decoding complex at ambient temperature

SM: PAR PAR PAR PAR PAR

Structure of complex 6cfk

6cfk

Crystal structure of the Thermus thermophilus 70S ribosome in complex with D-histidyl-CAM and bound to protein Y (YfiA) at 2.7A resolution

SM: ARG ARG EZP EZP

Structure of complex 6cfl

6cfl

Crystal structure of the Thermus thermophilus 70S ribosome in complex with lysyl-CAM and bound to protein Y (YfiA) at 2.6A resolution

SM: ARG ARG EZM EZM

Structure of complex 6czr

6czr

The structure of amicetin bound to the 70S ribosome

SM: ARG ARG FSD FSD