Complex 5wwr
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.10 |
| System mass | 154.92 kDa |
| Deposition year | 2017 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 5wwr |
| Reference | Liu Ru-Juan, Long Tao, Li Jing, Li Hao, Wang En-Duo. 2017. Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6 Nucleic Acids Research |
| Equivalence Class |
NR_all_99471.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SFG |
| Residue | . / 501 |
| Chain | E / A |
| Non-redundant | True |
| Interacting RNA chains | C/C |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | C/C: tRNA |
| RNA family global | tRNA |
| Volume | 314.19 Å3 |
| Hydrophobicity | 1.212 |
| Hydrophilicity | 1.173 |
| Buriedness | 0.935 |
| Don/acc character | 0.858 |
| SiteScore | 1.158 |
| D Score | 1.119 |
| Kd | — |
| Compound | SFG |
| Residue | . / 501 |
| Chain | F / B |
| Non-redundant | False |
| Interacting RNA chains | D/D |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | D/D: tRNA |
| RNA family global | tRNA |
| Volume | 336.48 Å3 |
| Hydrophobicity | 0.851 |
| Hydrophilicity | 1.193 |
| Buriedness | 0.920 |
| Don/acc character | 0.849 |
| SiteScore | 1.148 |
| D Score | 1.103 |
| Kd | — |