Complex 5ju8
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.60 |
| System mass | 2198.88 kDa |
| Deposition year | 2016 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 5ju8 |
| Reference | Arenz Stefan, Bock Lars V., Graf Michael, Innis C. Axel, Beckmann Roland, Grubmüller Helmut, Vaiana Andrea C., Wilson Daniel N.. 2016. A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest Nature Communications |
| Equivalence Class |
NR_all_83717.187
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | ERY |
| Residue | . / 9000 |
| Chain | EB / BA |
| Non-redundant | True |
| Interacting RNA chains | Y/BA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | Y/BA: rRNA |
| RNA family global | rRNA |
| Volume | 652.39 Å3 |
| Hydrophobicity | 0.550 |
| Hydrophilicity | 1.200 |
| Buriedness | 0.833 |
| Don/acc character | 1.756 |
| SiteScore | 1.240 |
| D Score | 1.049 |
| Kd | — |