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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 5lmv

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 4.90
System mass 913.50 kDa
Deposition year 2016
Molecule type RNA/Protein
# RNA entities 1
Organism Thermus
RCSB PDB Entry 5lmv
Reference Hussain Tanweer, Llácer Jose L., Wimberly Brian T., Kieft Jeffrey S., Ramakrishnan V.. 2016. Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation Cell
Equivalence Class NR_all_35542.167
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound FME
Residue . / 101
Chain DA / Z
Non-redundant True
Interacting RNA chains Y/Z
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains Y/Z: tRNA
RNA family global tRNA
Volume 96.04 Å3
Hydrophobicity 0.294
Hydrophilicity 0.774
Buriedness 0.565
Don/acc character 0.367
SiteScore 0.669
D Score 0.651
Kd