Complex 5kal
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.75 |
| System mass | 81.98 kDa |
| Deposition year | 2016 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Trypanosoma |
| RCSB PDB Entry | 5kal |
| Reference | Rajappa-Titu Lional, Suematsu Takuma, Munoz-Tello Paola, Long Marius, Demir Özlem, Cheng Kevin J., Stagno Jason R., Luecke Hartmut, Amaro Rommie E., Aphasizheva Inna, Aphasizhev Ruslan, Thore Stéphane. 2016. RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting Nucleic Acids Research |
| Equivalence Class |
NR_all_21736.11
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | UTP |
| Residue | . / 501 |
| Chain | E / A |
| Non-redundant | True |
| Interacting RNA chains | C/Y |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | C/Y: unknown |
| RNA family global | unknown |
| Volume | 686.00 Å3 |
| Hydrophobicity | 0.498 |
| Hydrophilicity | 1.302 |
| Buriedness | 0.819 |
| Don/acc character | 0.555 |
| SiteScore | 1.081 |
| D Score | 1.007 |
| Kd | — |
| Compound | UTP |
| Residue | . / 401 |
| Chain | G / B |
| Non-redundant | False |
| Interacting RNA chains | D/Z |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | D/Z: unknown |
| RNA family global | unknown |
| Volume | 677.43 Å3 |
| Hydrophobicity | 0.586 |
| Hydrophilicity | 1.395 |
| Buriedness | 0.848 |
| Don/acc character | 0.442 |
| SiteScore | 1.100 |
| D Score | 0.994 |
| Kd | — |