Complex 5lks
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.60 |
| System mass | 3818.88 kDa |
| Deposition year | 2016 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 5lks |
| Reference | Myasnikov Alexander G., Kundhavai Natchiar S., Nebout Marielle, Hazemann Isabelle, Imbert Véronique, Khatter Heena, Peyron Jean-François, Klaholz Bruno P.. 2016. Structure–function insights reveal the human ribosome as a cancer target for antibiotics Nature Communications |
| Equivalence Class |
NR_all_65061.63
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 3HE |
| Residue | . / 5101 |
| Chain | CC / L5 |
| Non-redundant | True |
| Interacting RNA chains | A/L5 |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | A/L5: rRNA |
| RNA family global | rRNA |
| Volume | 274.40 Å3 |
| Hydrophobicity | 0.376 |
| Hydrophilicity | 1.166 |
| Buriedness | 0.632 |
| Don/acc character | 1.016 |
| SiteScore | 1.041 |
| D Score | 0.856 |
| Kd | — |