Harnessing RIBOnucleic acid - Small molecules Structures
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNALys with U-G mismatch in the A-site
SM: SPE
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site
Structure of RelA bound to the 70S ribosome
SM: PAR
Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2
SM: GCP
High-resolution structure of the Escherichia coli ribosome
SM: 1PE PG4
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic
SM: 6EK
Structure of the WT E coli ribosome bound to tetracycline
SM: 1PE PG4 TAC
Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline
Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA
Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline
SM: 1PE PG4 T1C
Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome
Structure of the Wild-type 70S E coli ribosome bound to Tigecycline
Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA
Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA
SM: ERY
Cryo-EM structure of an ErmBL-stalled ribosome in complex with P-, and E-tRNA
Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit)
SM: GDP
Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit)
Structure-function insights reveal the human ribosome as a cancer target for antibiotics
SM: 3HE
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)
SM: GNP
Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.
Nonstop ribosomal complex bound with Dom34 and Hbs1
Crystal structure of Agelastatin A bound to the 80S ribosome
SM: 7MB
Crystal structure of geneticin (G418) bound to the yeast 80S ribosome
SM: GET
Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking)
SM: 8UZ
Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA
Crystal structure of Paromomycin bound to the yeast 80S ribosome
Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02
SM: 95H EPE
Crystal structure of Gentamicin bound to the yeast 80S ribosome
SM: LLL
Crystal structure of haemanthamine bound to the 80S ribosome
SM: HN8
Elongation factor G-ribosome complex captures in the absence of inhibitors.
Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome
SM: 7AL
Methicillin sensitive Staphylococcus aureus 70S ribosome
Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro
SM: PHE SPS
Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine
SM: YMZ
70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II)
SM: FME
70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III)
70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)
70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc)
Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog
SM: 917
Thermus thermophilus 70S ribosome lacking ribosomal protein uS17
SM: ARG
Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
SM: M2D
70S ribosome-EF-Tu H84A complex with GppNHp
SM: FME GNP PHE
70S ribosome-EF-Tu wt complex with GppNHp
70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA
SM: FME PHE
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3)
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4)
SM: FME GTP PHE
Crystal structure of the Thermus thermophilus 70S ribosome in complex with methymycin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution
SM: MT9
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pikromycin and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution
SM: AQJ
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
SM: B6M
Crystal structure of the Homo Sapiens cytoplasmic ribosomal decoding site in complex with G418
Crystal structure of the bacterial ribosomal decoding site in complex with 6'-fluoro sisomicin
SM: FSJ
Crystal structure of the protozoal cytoplasmic ribosomal decoding site in complex with 6'-fluoro sisomicin
Crystal structure of the Homo Sapiens cytoplasmic ribosomal decoding site in complex with G418 (P21212 form)
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site in complex with geneticin
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site in complex with paromomycin
Current selection range: to