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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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964 RNA-SM complexes found
filters used:  RNA family global: rRNA  
Structure of complex 5dox

5dox

Crystal structure of the Thermus thermophilus 70S ribosome in complex with Hygromycin-A at 3.1A resolution

SM: HGR HGR

Structure of complex 5el6

5el6

Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the first position and antibiotic paromomycin

SM: PAR PAR

Structure of complex 5el7

5el7

Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the second position and antibiotic paromomycin

SM: PAR PAR

Structure of complex 5fcj

5fcj

Structure of the anisomycin-containing uL3 W255C mutant 80S yeast ribosome

SM: ANM

Structure of complex 5fdu

5fdu

Crystal structure of the Metalnikowin I antimicrobial peptide bound to the Thermus thermophilus 70S ribosome

SM: AMP

Structure of complex 5gak

5gak

Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A

SM: 3HE

Structure of complex 5hau

5hau

Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome

SM: GDP GDP

Structure of complex 5hkv

5hkv

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lincomycin

SM: 3QB

Structure of complex 5hl7

5hl7

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lefamulin

SM: 62B EPE

Structure of complex 5i4l

5i4l

Crystal structure of Amicoumacin A bound to the yeast 80S ribosome

SM: UAM

Structure of complex 5ib7

5ib7

Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin

SM: PAR SPE SPE

Structure of complex 5ib8

5ib8

Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNALys with U-G mismatch in the A-site

SM: SPE

Structure of complex 5ibb

5ibb

Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site

SM: SPE SPE SPE

Structure of complex 5iqr

5iqr

Structure of RelA bound to the 70S ribosome

SM: PAR

Structure of complex 5it7

5it7

Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2

SM: GCP

Structure of complex 5it8

5it8

High-resolution structure of the Escherichia coli ribosome

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4

Structure of complex 5iwa

5iwa

Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic

SM: 6EK

Structure of complex 5j5b

5j5b

Structure of the WT E coli ribosome bound to tetracycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 TAC TAC

Structure of complex 5j7l

5j7l

Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 TAC TAC TAC TAC

Structure of complex 5j88

5j88

Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4

Structure of complex 5j8a

5j8a

Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 T1C T1C

Structure of complex 5j8b

5j8b

Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome

SM: GCP

Structure of complex 5j91

5j91

Structure of the Wild-type 70S E coli ribosome bound to Tigecycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 T1C T1C

Structure of complex 5jc9

5jc9

Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4

Structure of complex 5jte

5jte

Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA

SM: ERY

Structure of complex 5ju8

5ju8

Cryo-EM structure of an ErmBL-stalled ribosome in complex with P-, and E-tRNA

SM: ERY

Structure of complex 5jup

5jup

Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit)

SM: GDP

Structure of complex 5juu

5juu

Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit)

SM: GDP

Structure of complex 5lks

5lks

Structure-function insights reveal the human ribosome as a cancer target for antibiotics

SM: 3HE

Structure of complex 5lzd

5lzd

Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)

SM: GNP

Structure of complex 5lzs

5lzs

Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B

SM: GDP

Structure of complex 5lzw

5lzw

Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.

SM: GCP

Structure of complex 5m1j

5m1j

Nonstop ribosomal complex bound with Dom34 and Hbs1

SM: GNP

Structure of complex 5mei

5mei

Crystal structure of Agelastatin A bound to the 80S ribosome

SM: 7MB 7MB

Structure of complex 5ndg

5ndg

Crystal structure of geneticin (G418) bound to the yeast 80S ribosome

SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET

Structure of complex 5ndj

5ndj

Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking)

SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ

Structure of complex 5ndk

5ndk

Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA

SM: 8UZ 8UZ 8UZ 8UZ

Structure of complex 5ndv

5ndv

Structure of complex 5ndw

5ndw

Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome

SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ

Structure of complex 5nrg

5nrg

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02

SM: 95H EPE

Structure of complex 5obm

5obm

Crystal structure of Gentamicin bound to the yeast 80S ribosome

SM: LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL

Structure of complex 5on6

5on6

Crystal structure of haemanthamine bound to the 80S ribosome

SM: HN8 HN8

Structure of complex 5ot7

5ot7

Elongation factor G-ribosome complex captures in the absence of inhibitors.

SM: GDP

Structure of complex 5tbw

5tbw

Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome

SM: 7AL 7AL

Structure of complex 5tcu

5tcu

Methicillin sensitive Staphylococcus aureus 70S ribosome

SM: PAR

Structure of complex 5tgm

5tgm

Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro

SM: PHE PHE SPS SPS

Structure of complex 5umd

5umd

Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine

SM: YMZ YMZ

Structure of complex 5v7q

5v7q

Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog

SM: 917

Structure of complex 5v8i

5v8i

Thermus thermophilus 70S ribosome lacking ribosomal protein uS17

SM: ARG ARG

Structure of complex 5vp2

5vp2

Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution

SM: M2D M2D

Structure of complex 5wdt

5wdt

70S ribosome-EF-Tu H84A complex with GppNHp

SM: FME GNP PHE

Structure of complex 5we4

5we4

70S ribosome-EF-Tu wt complex with GppNHp

SM: FME GNP PHE

Structure of complex 5we6

5we6

70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA

SM: FME PHE

Structure of complex 5wf0

5wf0

70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)

SM: FME PHE

Structure of complex 5wfk

5wfk

70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3)

SM: FME PHE

Structure of complex 5wfs

5wfs

70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4)

SM: FME GTP PHE

Structure of complex 5wis

5wis

Crystal structure of the Thermus thermophilus 70S ribosome in complex with methymycin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution

SM: MT9 MT9

Structure of complex 5wit

5wit

Crystal structure of the Thermus thermophilus 70S ribosome in complex with pikromycin and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution

SM: AQJ AQJ

Structure of complex 5wnt

5wnt

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: B6M

Structure of complex 5wnu

5wnu

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus

SM: B6M