Complex 5v7q
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.70 |
| System mass | 1458.45 kDa |
| Deposition year | 2017 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Mycobacterium |
| RCSB PDB Entry | 5v7q |
| Reference | Yang Kailu, Chang Jeng-Yih, Cui Zhicheng, Li Xiaojun, Meng Ran, Duan Lijun, Thongchol Jirapat, Jakana Joanita, Huwe Christoph M., Sacchettini James C., Zhang Junjie. 2017. Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis Nucleic Acids Research |
| Equivalence Class |
NR_all_35677.6
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 917 |
| Residue | . / 5001 |
| Chain | FA / A |
| Non-redundant | True |
| Interacting RNA chains | G/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | G/A: rRNA |
| RNA family global | rRNA |
| Volume | 690.46 Å3 |
| Hydrophobicity | 0.259 |
| Hydrophilicity | 1.222 |
| Buriedness | 0.759 |
| Don/acc character | 1.488 |
| SiteScore | 1.191 |
| D Score | 0.997 |
| Kd | — |