Complex 5gak
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.88 |
| System mass | 2016.97 kDa |
| Deposition year | 2015 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Saccharomyces |
| RCSB PDB Entry | 5gak |
| Reference | Schmidt Christian, Becker Thomas, Heuer André, Braunger Katharina, Shanmuganathan Vivekanandan, Pech Markus, Berninghausen Otto, Wilson Daniel N., Beckmann Roland. 2016. Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome Nucleic Acids Research |
| Equivalence Class |
NR_all_90506.85,
NR_all_45609.8
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 3HE |
| Residue | . / 3401 |
| Chain | XA / 1 |
| Non-redundant | True |
| Interacting RNA chains | A/1 |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/1: rRNA |
| RNA family global | rRNA |
| Volume | 433.21 Å3 |
| Hydrophobicity | 0.255 |
| Hydrophilicity | 1.327 |
| Buriedness | 0.851 |
| Don/acc character | 1.055 |
| SiteScore | 0.922 |
| D Score | 0.788 |
| Kd | — |