Complex 5hl7
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.55 |
| System mass | 1365.46 kDa |
| Deposition year | 2016 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Staphylococcus |
| RCSB PDB Entry | 5hl7 |
| Reference | Eyal Zohar, Matzov Donna, Krupkin Miri, Paukner Susanne, Riedl Rosemarie, Rozenberg Haim, Zimmerman Ella, Bashan Anat, Yonath Ada. 2016. A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism Scientific Reports |
| Equivalence Class |
NR_all_90633.30
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 62B |
| Residue | . / 3003 |
| Chain | IA / X |
| Non-redundant | True |
| Interacting RNA chains | B/X |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | B/X: rRNA |
| RNA family global | rRNA |
| Volume | 765.23 Å3 |
| Hydrophobicity | 0.481 |
| Hydrophilicity | 1.112 |
| Buriedness | 0.738 |
| Don/acc character | 1.576 |
| SiteScore | 1.177 |
| D Score | 1.020 |
| Kd | — |
| Compound | EPE |
| Residue | . / 201 |
| Chain | LU / N |
| Non-redundant | True |
| Interacting RNA chains | B/X |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | B/X: rRNA |
| RNA family global | rRNA |
| Volume | 497.69 Å3 |
| Hydrophobicity | 0.213 |
| Hydrophilicity | 1.735 |
| Buriedness | 0.907 |
| Don/acc character | 1.049 |
| SiteScore | 1.140 |
| D Score | 0.919 |
| Kd | — |