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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 5fdu

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 2.90
System mass 4368.31 kDa
Deposition year 2015
Molecule type RNA/Protein
# RNA entities 1
Organism Thermus
RCSB PDB Entry 5fdu
Reference Seefeldt A. Carolin, Graf Michael, Pérébaskine Natacha, Nguyen Fabian, Arenz Stefan, Mardirossian Mario, Scocchi Marco, Wilson Daniel N., Innis C. Axel. 2016. Structure of the mammalian antimicrobial peptide Bac7(1–16) bound within the exit tunnel of a bacterial ribosome Nucleic Acids Research
Equivalence Class NR_all_42622.80
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound AMP
Residue . / 3025
Chain JNA / 1B
Non-redundant True
Interacting RNA chains B/1B
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains B/1B: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd