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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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1215 RNA-SM complexes found
Structure of complex 4ycp

4ycp

E. coli dihydrouridine synthase C (DusC) in complex with tRNATrp

SM: FMN

Structure of complex 4yhh

4yhh

Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline

SM: T1C

Structure of complex 4z3s

4z3s

Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic A201A, mRNA and three tRNAs in the A, P and E sites at 2.65A resolution

SM: 4M2 4M2

Structure of complex 4zer

4zer

Crystal structure of the Onc112 antimicrobial peptide bound to the Thermus thermophilus 70S ribosome

SM: ARG

Structure of complex 5a0v

5a0v

Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family

SM: C5P

Structure of complex 5a9z

5a9z

Complex of Thermous thermophilus ribosome bound to BipA-GDPCP

SM: NMY NMY

Structure of complex 5aa0

5aa0

Complex of Thermous thermophilus ribosome (A-and P-site tRNA) bound to BipA-GDPCP

SM: 8AN NMY NMY

Structure of complex 5afi

5afi

2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM

SM: FME

Structure of complex 5axn

5axn

Crystal structure of Thg1 like protein (TLP) with tRNA(Phe) and GDPNP

SM: GNP

Structure of complex 5br8

5br8

Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin

SM: PAR PAR PAR PAR PAR PAR

Structure of complex 5cd1

5cd1

Structure of an asymmetric tetramer of human tRNA m1A58 methyltransferase in a complex with SAH and tRNA3Lys

SM: SAH SAH

Structure of complex 5dge

5dge

Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome

SM: SPS SPS

Structure of complex 5dgf

5dgf

Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog

SM: SPS SPS

Structure of complex 5dgv

5dgv

Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog

SM: SPS SPS

Structure of complex 5dm7

5dm7

Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with hygromycin A

SM: HGR

Structure of complex 5dox

5dox

Crystal structure of the Thermus thermophilus 70S ribosome in complex with Hygromycin-A at 3.1A resolution

SM: HGR HGR

Structure of complex 5doy

5doy

Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution

SM: HGR HGR

Structure of complex 5dto

5dto

Dengue virus full length NS5 complexed with viral Cap 0-RNA and SAH

SM: SAH

Structure of complex 5e6m

5e6m

Crystal structure of human wild type GlyRS bound with tRNAGly

SM: GAP GAP

Structure of complex 5el6

5el6

Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the first position and antibiotic paromomycin

SM: PAR PAR

Structure of complex 5el7

5el7

Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the second position and antibiotic paromomycin

SM: PAR PAR

Structure of complex 5f8i

5f8i

Enterovirus 71 Polymerase Elongation Complex (C1S2/3 Form)

SM: CTP

Structure of complex 5fcj

5fcj

Structure of the anisomycin-containing uL3 W255C mutant 80S yeast ribosome

SM: ANM

Structure of complex 5fdu

5fdu

Crystal structure of the Metalnikowin I antimicrobial peptide bound to the Thermus thermophilus 70S ribosome

SM: AMP

Structure of complex 5gak

5gak

Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A

SM: 3HE

Structure of complex 5gin

5gin

Crystal structure of box C/D RNP with 12 nt guide regions and 9 nt substrates

SM: SAH SAH SAH

Structure of complex 5gio

5gio

Crystal structure of box C/D RNP with 12 nt guide regions and 13 nt substrates

SM: SAH SAH SAH

Structure of complex 5gip

5gip

Crystal structure of box C/D RNP with 13 nt guide regions and 11 nt substrates

SM: SAH SAH SAH SAH

Structure of complex 5hau

5hau

Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome

SM: GDP GDP

Structure of complex 5hkv

5hkv

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lincomycin

SM: 3QB

Structure of complex 5hl7

5hl7

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lefamulin

SM: 62B EPE

Structure of complex 5i4l

5i4l

Crystal structure of Amicoumacin A bound to the yeast 80S ribosome

SM: UAM

Structure of complex 5ib7

5ib7

Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin

SM: PAR SPE SPE

Structure of complex 5ib8

5ib8

Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNALys with U-G mismatch in the A-site

SM: SPE

Structure of complex 5ibb

5ibb

Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site

SM: SPE SPE SPE

Structure of complex 5iqr

5iqr

Structure of RelA bound to the 70S ribosome

SM: PAR

Structure of complex 5it8

5it8

High-resolution structure of the Escherichia coli ribosome

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4

Structure of complex 5iwa

5iwa

Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic

SM: 6EK

Structure of complex 5j5b

5j5b

Structure of the WT E coli ribosome bound to tetracycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 TAC TAC

Structure of complex 5j7l

5j7l

Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 TAC TAC TAC TAC

Structure of complex 5j88

5j88

Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4

Structure of complex 5j8a

5j8a

Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 T1C T1C

Structure of complex 5j8b

5j8b

Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome

SM: GCP

Structure of complex 5j91

5j91

Structure of the Wild-type 70S E coli ribosome bound to Tigecycline

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 T1C T1C

Structure of complex 5jc9

5jc9

Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA

SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4

Structure of complex 5jte

5jte

Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA

SM: ERY

Structure of complex 5ju8

5ju8

Cryo-EM structure of an ErmBL-stalled ribosome in complex with P-, and E-tRNA

SM: ERY

Structure of complex 5jup

5jup

Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit)

SM: GDP

Structure of complex 5juu

5juu

Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit)

SM: GDP

Structure of complex 5kal

5kal

Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP and UpU

SM: UTP UTP

Structure of complex 5lks

5lks

Structure-function insights reveal the human ribosome as a cancer target for antibiotics

SM: 3HE

Structure of complex 5lmv

5lmv

Structure of bacterial 30S-IF1-IF2-IF3-mRNA-tRNA translation pre-initiation complex(state-III)

SM: FME

Structure of complex 5lzd

5lzd

Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)

SM: GNP

Structure of complex 5lzs

5lzs

Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B

SM: GDP

Structure of complex 5lzw

5lzw

Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.

SM: GCP

Structure of complex 5m1j

5m1j

Nonstop ribosomal complex bound with Dom34 and Hbs1

SM: GNP

Structure of complex 5mei

5mei

Crystal structure of Agelastatin A bound to the 80S ribosome

SM: 7MB 7MB

Structure of complex 5ndg

5ndg

Crystal structure of geneticin (G418) bound to the yeast 80S ribosome

SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET

Structure of complex 5ndj

5ndj

Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking)

SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ

Structure of complex 5ndk

5ndk

Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA

SM: 8UZ 8UZ 8UZ 8UZ