Complex 5afi
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.90 |
| System mass | 2302.71 kDa |
| Deposition year | 2015 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 5afi |
| Reference | Fischer Niels, Neumann Piotr, Konevega Andrey L., Bock Lars V., Ficner Ralf, Rodnina Marina V., Stark Holger. 2015. Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM Nature |
| Equivalence Class |
NR_all_35542.167,
NR_all_83717.187
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | FME |
| Residue | . / 105 |
| Chain | RE / v |
| Non-redundant | True |
| Interacting RNA chains | AA/A, V/v |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | V/v: tRNA, AA/A: rRNA |
| RNA family global | multiple |
| Volume | 618.77 Å3 |
| Hydrophobicity | 0.491 |
| Hydrophilicity | 1.006 |
| Buriedness | 0.753 |
| Don/acc character | 3.603 |
| SiteScore | 1.194 |
| D Score | 1.064 |
| Kd | — |