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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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855 RNA-SM complexes found
Structure of complex 8y5o

8y5o

E.coli transcription translation coupling complex in TTC-B state 3 (subclass1) containing mRNA with 30-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8y5p

8y5p

E.coli transcription translation coupling complex in TTC-B state 4 (subclass 1) containing mRNA with 24-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8y5q

8y5q

E.coli transcription translation coupling complex in TTC-B state 4 (subclass 2) containing mRNA with 27-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and GDPCP

SM: GCP

Structure of complex 8ydg

8ydg

E.coli transcription translation coupling complex in TTC-B state 3 (subclass2) containing mRNA with 39-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8ydj

8ydj

E.coli transcription translation coupling complex in TTC-P containing mRNA with 39-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8z8x

8z8x

Cryo-EM structure of Thogoto virus polymerase in a transcription initiation conformation

SM: G2P

Structure of complex 8z90

8z90

Cryo-EM structure of Thogoto virus polymerase in transcription initiation conformation 2

SM: G2P

Structure of complex 9avr

9avr

Human eIF4A-1 in complex with AMP-PNP, RNA, and the inhibitor silvestrol

SM: A1AG8

Structure of complex 9blf

9blf

SARS-CoV-2 core polymerase complex inhibited by araCTP

SM: HF4

Structure of complex 9bs0

9bs0

YphC-treated 45SYphC particle. Class 5

SM: GNP

Structure of complex 9c3h

9c3h

Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site.

SM: B3P

Structure of complex 9d0g

9d0g

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with O-cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution

SM: A1A1F A1A1F

Structure of complex 9d0h

9d0h

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with C-cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution

SM: A1A1J A1A1J

Structure of complex 9d0i

9d0i

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with Se-cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.45A resolution

SM: A1A1K A1A1K

Structure of complex 9d0j

9d0j

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with BT-33, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.50A resolution

SM: A1A1L A1A1L

Structure of complex 9dts

9dts

Crystal structure of the human eIF4A1/AMPPNP/amidino-rocaglate/polypurine RNA complex

SM: A1BB1 A1BB1 A1BB1 A1BB1

Structure of complex 9e6q

9e6q

Cryo-EM structure of the Pyrobaculum calidifontis 50S ribosomal subunit in complex with Dri

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9e71

9e71

Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9e7f

9e7f

Cryo-EM structure of the Pyrobaculum calidifontis 70S ribosome in complex with Dri

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9evs

9evs

Structure of the flowering plant mitoribosome with P-site tRNA

SM: CLM

Structure of complex 9ey1

9ey1

Human mitochondrial RNase Z with tRNA-His precursor

SM: GTP

Structure of complex 9f1b

9f1b

Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E

SM: SPM SPM SPM

Structure of complex 9f1c

9f1c

Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E

SM: SPM SPM SPM

Structure of complex 9f1d

9f1d

Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK

SM: SPM SPM SPM

Structure of complex 9fhl

9fhl

High-resolution cryo-EM structure of Saccharolobus solfataricus 30S ribosomal subunit bound to mRNA and initiator tRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fib

9fib

Structure of 30S-IF1-IF3-mRNA-GE81112A complex

SM: A1IC4

Structure of complex 9fqz

9fqz

CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1

SM: 3HE ANM GDP HYG

Structure of complex 9fra

9fra

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9frk

9frk

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9frl

9frl

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fs6

9fs6

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fs8

9fs8

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aEF1A-like mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fsf

9fsf

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fxo

9fxo

CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA : LM32CS1C1 M2 OE MUTANT

SM: PAR PAR PAR PAR PAR PAR

Structure of complex 9fy0

9fy0

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9g06

9g06

Structure of 30S-IF1-IF3-mRNA-fMet-tRNA-GE81112A complex

SM: A1IC4

Structure of complex 9g1z

9g1z

Structure of Candida albicans 80S ribosome in complex with mefloquine (non-rotated state)

SM: SPK YMZ YMZ

Structure of complex 9g30

9g30

The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) shows strong density for the A site tRNA

SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET SPK

Structure of complex 9g5d

9g5d

Assembly intermediate of human mitochondrial ribosome small subunit (State C)

SM: NAD

Structure of complex 9g6j

9g6j

The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) with strong density for the P-site tRNA

SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET SPK YMZ

Structure of complex 9gju

9gju

Structure of replicating Nipah Virus RNA Polymerase Complex - RNA-bound state

SM: GNP

Structure of complex 9gmo

9gmo

eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16

SM: EPE

Structure of complex 9gms

9gms

Mtb PNPase Rv2783c

SM: A1IM2 A1IM2 A1IM2

Structure of complex 9gmt

9gmt

Mtb PNPase Rv2783c Mutant L328F

SM: A1IM2 A1IM2 A1IM2

Structure of complex 9h3g

9h3g

Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs and mRNA

SM: EPE TER

Structure of complex 9h51

9h51

Assembly intermediate of human mitochondrial ribosome small subunit in complex with PUS1, METTL15 and RBFA(IN conformation) (state M1)

SM: NAD SPM

Structure of complex 9h6i

9h6i

Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs, mRNA, and thermospermine

SM: EPE TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER

Structure of complex 9h8g

9h8g

Complex 5 30S-GE81112

SM: A1IC4

Structure of complex 9h90

9h90

Cryo-EM structure of the Vibrio natrigens 30S ribosomal subunit in complex with spectinomycin.

SM: SCM

Structure of complex 9h9h

9h9h

Complex 1 30S-IF1-IF2-IF3-GE81112

SM: A1IC4

Structure of complex 9h9j

9h9j

Complex 2 (BODY) 30S-IF1-IF3-tRNA-GE81112

SM: A1IC4

Structure of complex 9h9l

9h9l

Complex 3 (BODY) 30S-tRNA-GE81112

SM: A1IC4

Structure of complex 9h9n

9h9n

Complex 4 (BODY) 30S-GE81112 (weak residual tRNA)

SM: A1IC4

Structure of complex 9hcg

9hcg

Mouse mitoribosome large subunit assembly intermediate bound to NSUN4, METRF4, MRM2, GTPBP7 and MALSU1-L0R8F8-mt-ACP complex, State D (SAMC knock-out)

SM: SAH

Structure of complex 9hes

9hes

Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs, mRNA, and thermospermine

SM: EPE TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER

Structure of complex 9hmw

9hmw

Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs and mRNA

SM: EPE TER

Structure of complex 9i1w

9i1w

High resolution structure of the thermophilic 60S ribosomal subunit of Chaetomium thermophilum

SM: SPM SPM

Structure of complex 9imb

9imb

The crystal structure of human m5C methyltransferase NSUN6 bound to its S-adenosyl-L-methionine analog and a NECTIN-2 3'-UTR RNA substrate

SM: SFG SFG

Structure of complex 9j5p

9j5p

Crystal structure of B. subtilis CspR complexed with sinefungin and cellularly expressed tRNA Leu

SM: SFG

Structure of complex 9l5r

9l5r

Cryo-EM structure of the thermophile spliceosome (state ILS)

SM: M7M