Complex 9fxo
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.25 |
| System mass | 3633.51 kDa |
| Deposition year | 2024 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Leishmania |
| RCSB PDB Entry | 9fxo |
| Equivalence Class |
NR_all_82920.5,
NR_all_46927.6
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | PAR |
| Residue | . / 1978 |
| Chain | GJ / L1 |
| Non-redundant | True |
| Interacting RNA chains | A/L1 |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/L1: rRNA |
| RNA family global | rRNA |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | PAR |
| Residue | . / 1728 |
| Chain | EO / L2 |
| Non-redundant | True |
| Interacting RNA chains | B/L2 |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | B/L2: rRNA |
| RNA family global | rRNA |
| Volume | 657.53 Å3 |
| Hydrophobicity | 0.428 |
| Hydrophilicity | 1.004 |
| Buriedness | 0.728 |
| Don/acc character | 1.451 |
| SiteScore | 1.027 |
| D Score | 1.049 |
| Kd | — |
| Compound | PAR |
| Residue | . / 1729 |
| Chain | FO / L2 |
| Non-redundant | True |
| Interacting RNA chains | YA/S1, B/L2 |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | B/L2: rRNA, YA/S1: rRNA |
| RNA family global | rRNA |
| Volume | 212.66 Å3 |
| Hydrophobicity | 0.157 |
| Hydrophilicity | 1.136 |
| Buriedness | 0.712 |
| Don/acc character | 1.083 |
| SiteScore | 0.814 |
| D Score | 0.554 |
| Kd | — |
| Compound | PAR |
| Residue | . / 208 |
| Chain | UP / L7 |
| Non-redundant | True |
| Interacting RNA chains | G/L7, A/L1 |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/L1: rRNA, G/L7: rRNA |
| RNA family global | rRNA |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | PAR |
| Residue | . / 2445 |
| Chain | OW / S1 |
| Non-redundant | True |
| Interacting RNA chains | YA/S1 |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | YA/S1: rRNA |
| RNA family global | rRNA |
| Volume | 167.38 Å3 |
| Hydrophobicity | 0.064 |
| Hydrophilicity | 1.084 |
| Buriedness | 0.700 |
| Don/acc character | 1.174 |
| SiteScore | 0.604 |
| D Score | 0.497 |
| Kd | — |
| Compound | PAR |
| Residue | . / 2446 |
| Chain | PW / S1 |
| Non-redundant | True |
| Interacting RNA chains | YA/S1 |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | YA/S1: rRNA |
| RNA family global | rRNA |
| Volume | 50.76 Å3 |
| Hydrophobicity | 0.000 |
| Hydrophilicity | 1.098 |
| Buriedness | 0.587 |
| Don/acc character | 1.556 |
| SiteScore | 0.447 |
| D Score | 0.320 |
| Kd | — |