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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9bs0

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.30
System mass 1345.01 kDa
Deposition year 2024
Molecule type RNA/Protein
# RNA entities 1
Organism Bacillus
RCSB PDB Entry 9bs0
Reference Arpin Dominic, Palacios Armando, Basu Kaustuv, Ortega Joaquin. 2025. The binding of RbgA to a critical 50S assembly intermediate facilitates YphC function in bacterial ribosomal assembly Nucleic Acids Research
Equivalence Class NR_all_41610.25
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound GNP
Residue . / 502
Chain AA / W
Non-redundant True
Interacting RNA chains A/A
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains A/A: rRNA
RNA family global rRNA
Volume 421.20 Å3
Hydrophobicity 0.191
Hydrophilicity 1.614
Buriedness 0.788
Don/acc character 0.537
SiteScore 1.060
D Score 0.886
Kd