HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Compound B3P

Identifiers

  • Canonical SMILES: 
    OCC(CO)(CO)NCCCNC(CO)(CO)CO
  • IUPAC name: 
    2,2'-(propane-1,3-diyldiimino)bis[2-(hydroxymethyl)propane-1,3-diol]
  • InChi: 
    InChI=1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2
  • InChiKey: 
    HHKZCCWKTZRCCL-UHFFFAOYSA-N

Chemistry rules

Lipinski's RO5 Veber Pfizer's 3/75

External links

125132 CHEMBL63859 DB02676

RNA-SM complexes

PDB code Deposition date Reference publication
7uoo April 13, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7uoo April 13, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7uoo April 13, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7uqb April 19, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7uqb April 19, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7uqb April 19, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7uqz April 20, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7uqz April 20, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7uqz April 20, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7v08 May 10, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7v08 May 10, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
7v08 May 10, 2022 Sekulski Kamil, Cruz Victor Emmanuel, Weirich Christine S., Erzberger Jan P.. . rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly Nature Communications
9c3h June 1, 2024 Zhu Xiaoqiang, Cruz Victor Emmanuel, Zhang He, Erzberger Jan P., Mendell Joshua T.. . Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes Science

Physicochemical filters

Descriptor Lipinski's RO5 Veber Pfizer's 3/75
Compliance
MW 282.33 g/mol
HBA not available
HBD not available
HBA + HBD
AlogP not available
TPSA not available
RB not available

Radar chart