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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9gju

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 2.80
System mass 578.53 kDa
Deposition year 2024
Molecule type RNA/Protein
# RNA entities 1
Organism Henipavirus
RCSB PDB Entry 9gju
Reference Sala Fernanda A., Ditter Katja, Dybkov Olexandr, Urlaub Henning, Hillen Hauke S.. 2025. Structural basis of Nipah virus RNA synthesis Nature Communications
Equivalence Class NR_all_03353.1
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound GNP
Residue . / 2301
Chain H / A
Non-redundant True
Interacting RNA chains D/F, E/G
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains D/F: unknown, E/G: unknown
RNA family global unknown
Volume 726.82 Å3
Hydrophobicity 0.548
Hydrophilicity 1.346
Buriedness 0.874
Don/acc character 0.906
SiteScore 1.117
D Score 1.026
Kd