Complex 9avr
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 1.91 |
| System mass | 50.97 kDa |
| Deposition year | 2024 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 9avr |
| Reference | Naineni Sai Kiran, Bhatt Garvit, Jiramongkolsiri Ekkanat, Robert Francis, Cencic Regina, Huang Sidong, Nagar Bhushan, Pelletier Jerry. 2024. Protein–RNA interactions mediated by silvestrol—insight into a unique molecular clamp Nucleic Acids Research |
| Equivalence Class |
NR_all_45897.2
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | A1AG8 |
| Residue | . / 101 |
| Chain | G / B |
| Non-redundant | False |
| Interacting RNA chains | B/B |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | B/B: unknown |
| RNA family global | unknown |
| Volume | 213.00 Å3 |
| Hydrophobicity | 1.192 |
| Hydrophilicity | 0.498 |
| Buriedness | 0.604 |
| Don/acc character | 1.376 |
| SiteScore | 0.952 |
| D Score | 1.025 |
| Kd | — |