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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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93 RNA-SM complexes found
Structure of complex 12dp

12dp

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with sparsomycin, mRNA, and aminoacylated initiator P-site fMet-tRNAmet at 2.95A resolution

SM: SPS SPS

Structure of complex 12dq

12dq

Crystal structure of Thermus thermophilus 70S ribosome in complex with sparsomycin, protein Y, and P-site MTI-tripeptidyl-tRNA analog ACCA-ITM at 2.75A resolution

SM: ARG SPS

Structure of complex 1hnx

1hnx

STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH PACTAMYCIN

SM: PCY

Structure of complex 1hnz

1hnz

STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH HYGROMYCIN B

SM: HYG

Structure of complex 4khp

4khp

Structure of the Thermus thermophilus 30S ribosomal subunit in complex with de-6-MSA-pactamycin

SM: PAR PAR PAR PAR PAR PAR PAR PCY

Structure of complex 4v9q

4v9q

Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome.

SM: BLS BLS

Structure of complex 4w2f

4w2f

Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites

SM: UAM UAM

Structure of complex 4w2g

4w2g

Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites

SM: PCY PCY

Structure of complex 4w2h

4w2h

Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site

SM: PCY PCY

Structure of complex 4w2i

4w2i

Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites

SM: NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG NEG

Structure of complex 4wt8

4wt8

Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex

SM: 3V6 3V6 PAR PAR

Structure of complex 4z3s

4z3s

Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic A201A, mRNA and three tRNAs in the A, P and E sites at 2.65A resolution

SM: 4M2 4M2

Structure of complex 5aa0

5aa0

Complex of Thermous thermophilus ribosome (A-and P-site tRNA) bound to BipA-GDPCP

SM: 8AN NMY NMY

Structure of complex 5afi

5afi

2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM

SM: FME

Structure of complex 5dgv

5dgv

Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog

SM: SPS SPS

Structure of complex 5doy

5doy

Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution

SM: HGR HGR

Structure of complex 5o61

5o61

The complete structure of the Mycobacterium smegmatis 70S ribosome

SM: PHE

Structure of complex 5tgm

5tgm

Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro

SM: PHE PHE SPS SPS

Structure of complex 5uyl

5uyl

70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II)

SM: FME

Structure of complex 5uym

5uym

70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III)

SM: FME

Structure of complex 5uyp

5uyp

70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)

SM: FME

Structure of complex 5uyq

5uyq

70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc)

SM: FME

Structure of complex 5wdt

5wdt

70S ribosome-EF-Tu H84A complex with GppNHp

SM: FME GNP PHE

Structure of complex 5we4

5we4

70S ribosome-EF-Tu wt complex with GppNHp

SM: FME GNP PHE

Structure of complex 6b4v

6b4v

Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome

SM: BLS BLS

Structure of complex 6boh

6boh

Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome

SM: BLS BLS

Structure of complex 6of6

6of6

Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site

SM: AMP PAR PAR

Structure of complex 6qul

6qul

Structure of a bacterial 50S ribosomal subunit in complex with the novel quinoxolidinone antibiotic cadazolid

SM: AMP JJH

Structure of complex 6zsa

6zsa

Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA

SM: DOL

Structure of complex 6zsb

6zsb

Human mitochondrial ribosome in complex with mRNA and P-site tRNA

SM: DOL

Structure of complex 6zse

6zse

Human mitochondrial ribosome in complex with mRNA, A/P-tRNA and P/E-tRNA

SM: DOL

Structure of complex 6zsg

6zsg

Human mitochondrial ribosome in complex with mRNA, A-site tRNA, P-site tRNA and E-site tRNA

SM: DOL

Structure of complex 7b5k

7b5k

E. coli 70S containing suppressor tRNA in the A-site stabilized by a Negamycin analogue and P-site tRNA-nascent chain.

SM: ERY SY5 SY5

Structure of complex 7lh5

7lh5

Crystal structure of the Thermus thermophilus 70S ribosome in complex with plazomicin, mRNA and tRNAs

SM: EDS EDS

Structure of complex 7nwg

7nwg

Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S.

SM: BLS

Structure of complex 7nwi

7nwi

Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S

SM: BLS

Structure of complex 7rq8

7rq8

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with iboxamycin, mRNA, deacylated A- and E-site tRNAs, and aminoacylated P-site tRNA at 2.50A resolution

SM: 6IF 6IF

Structure of complex 7rq9

7rq9

Crystal structure of the A2058-dimethylated Thermus thermophilus 70S ribosome in complex with iboxamycin, mRNA, deacylated A- and E-site tRNAs, and aminoacylated P-site tRNA at 2.60A resolution

SM: 6IF 6IF

Structure of complex 7s1g

7s1g

wild-type Escherichia coli stalled ribosome with antibiotic linezolid

SM: ZLD

Structure of complex 7s1i

7s1i

Wild-type Escherichia coli stalled ribosome with antibiotic radezolid

SM: RD8

Structure of complex 7s1k

7s1k

Cfr-modified Escherichia coli stalled ribosome with antibiotic radezolid

SM: RD8

Structure of complex 7tql

7tql

CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B.

SM: 5GP

Structure of complex 7u2i

7u2i

Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, aminoacylated P-site fMet-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution

SM: CLM CLM

Structure of complex 7u2j

7u2j

Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, peptidyl P-site fMAC-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution

SM: CLM CLM

Structure of complex 7ych

7ych

Cryo-EM structure of Tetrahymena ribozyme conformation 3 undergoing the first-step self-splicing

SM: GTP

Structure of complex 7zta

7zta

Structure of an Escherichia coli 70S ribosome stalled by Tetracenomycin X during translation of an MAAAPQK(C) peptide

SM: OCW

Structure of complex 8crx

8crx

Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound

SM: V7A V7A

Structure of complex 8ev6

8ev6

Crystal structure of the Thermus thermophilus 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs

SM: AKN AKN AKN AKN AKN AKN AKN AKN

Structure of complex 8fto

8fto

E. coli 70S ribosome with an improved MS2 tag inserted in H98

SM: FME

Structure of complex 8g2b

8g2b

Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with iboxamycin, mRNA, deacylated A- and E-site tRNAphe, and aminoacylated P-site fMet-tRNAmet at 2.55A resolution

SM: 6IF 6IF

Structure of complex 8g4s

8g4s

40S ribosomal subunit of the 80S Giardia intestinalis assemblage A ribosome with Emetine bound in V2 conformation with mRNA and three tRNAs.

SM: YAT

Structure of complex 8g6j

8g6j

mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)

SM: 3HE GSP HMT

Structure of complex 8ifc

8ifc

Arbekacin-bound E.coli 70S ribosome in the PURE system

SM: 84G 84G 84G 84G 84G 84G 84G 84G 84G 84G SPM

Structure of complex 8k2c

8k2c

Cryo-EM structure of the human 80S ribosome with Tigecycline

SM: T1C T1C T1C T1C T1C T1C T1C T1C T1C

Structure of complex 8qk7

8qk7

E167K RF2 on E. coli 70S release complex with UAA

SM: SPM SPM

Structure of complex 8rri

8rri

Human mitochondrial ribosome in complex with antibiotic tigecycline

SM: T1C T1C T1C

Structure of complex 8rxh

8rxh

CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN

SM: A1H4F

Structure of complex 8syl

8syl

Cryo-EM structure of the Escherichia coli 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs

SM: AKN AKN

Structure of complex 8ud6

8ud6

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.70A resolution

SM: WC9 WC9

Structure of complex 8ud7

8ud7

Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.70A resolution

SM: WC9 WC9