Complex 1hnz
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.30 |
| System mass | 788.32 kDa |
| Deposition year | 2000 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 1hnz |
| Reference | Brodersen Ditlev E., Clemons William M., Carter Andrew P., Morgan-Warren Robert J., Wimberly Brian T., Ramakrishnan V.. 2000. The Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit Cell |
| Equivalence Class |
NR_all_65795.87,
NR_all_31741.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | HYG |
| Residue | . / 1632 |
| Chain | MD / A |
| Non-redundant | False |
| Interacting RNA chains | B/X, A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: rRNA, B/X: mRNA |
| RNA family global | multiple |
| Volume | 118.34 Å3 |
| Hydrophobicity | 0.198 |
| Hydrophilicity | 0.952 |
| Buriedness | 0.563 |
| Don/acc character | 2.013 |
| SiteScore | 0.825 |
| D Score | 0.644 |
| Kd | — |