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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 6zsg

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 4.00
System mass 3089.43 kDa
Deposition year 2020
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 6zsg
Reference Aibara Shintaro, Singh Vivek, Modelska Angelika, Amunts Alexey. 2020. Structural basis of mitochondrial translation eLife
Equivalence Class NR_all_12763.37
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound DOL
Residue . / 5143
Chain FI / XA
Non-redundant True
Interacting RNA chains GC/r3, FC/r2, K/XA
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains K/XA: rRNA, FC/r2: tRNA, GC/r3: tRNA
RNA family global multiple
Volume 656.50 Å3
Hydrophobicity 0.418
Hydrophilicity 1.009
Buriedness 0.762
Don/acc character 1.731
SiteScore 1.199
D Score 1.068
Kd