HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8k2c

System information

Experimental technique Electron Microscopy
Experimental resolution 2.40
System mass 4008.39 kDa
Deposition year 2023
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 8k2c
Reference Li Xiang, Wang Mengjiao, Denk Timo, Buschauer Robert, Li Yi, Beckmann Roland, Cheng Jingdong. . Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline Nature Communications

Compound T1C
Residue . / 5312
Chain LK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 494.26 Å3
Hydrophobicity 0.214
Hydrophilicity 1.358
Buriedness 0.681
Don/acc character 0.772
SiteScore 1.139
D Score 0.906

Compound T1C
Residue . / 5313
Chain MK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 289.15 Å3
Hydrophobicity 0.083
Hydrophilicity 1.508
Buriedness 0.656
Don/acc character 0.730
SiteScore 0.903
D Score 0.748

Compound T1C
Residue . / 5314
Chain NK / L5
Non-redundant True
Interacting RNA chains A/L5, C/L8
Volume 641.75 Å3
Hydrophobicity 0.093
Hydrophilicity 1.348
Buriedness 0.673
Don/acc character 1.221
SiteScore 1.133
D Score 0.904

Compound T1C
Residue . / 5315
Chain OK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 431.49 Å3
Hydrophobicity 0.154
Hydrophilicity 1.654
Buriedness 0.700
Don/acc character 0.863
SiteScore 1.001
D Score 0.821

Compound T1C
Residue . / 5316
Chain PK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 311.10 Å3
Hydrophobicity 0.035
Hydrophilicity 1.430
Buriedness 0.665
Don/acc character 1.788
SiteScore 0.975
D Score 0.868

Compound T1C
Residue . / 5317
Chain QK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 481.23 Å3
Hydrophobicity 0.433
Hydrophilicity 0.943
Buriedness 0.658
Don/acc character 2.284
SiteScore 0.992
D Score 1.027

Compound T1C
Residue . / 5318
Chain RK / L5
Non-redundant True
Interacting RNA chains A/L5
Volume 164.30 Å3
Hydrophobicity 0.020
Hydrophilicity 1.349
Buriedness 0.679
Don/acc character 2.326
SiteScore 0.831
D Score 0.707

Compound T1C
Residue . / 1930
Chain SM / S2
Non-redundant True
Interacting RNA chains GC/CC, WA/S2
Volume 433.90 Å3
Hydrophobicity 0.657
Hydrophilicity 1.283
Buriedness 0.819
Don/acc character 0.831
SiteScore 1.081
D Score 1.013

Compound T1C
Residue . / 101
Chain XM / CC
Non-redundant True
Interacting RNA chains A/L5, GC/CC
Volume 72.03 Å3
Hydrophobicity 0.212
Hydrophilicity 0.709
Buriedness 0.552
Don/acc character 1.164
SiteScore 0.526
D Score 0.476