HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 5o61

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.31
System mass 2322.20 kDa
Deposition year 2017
Molecule type RNA/Protein
# RNA entities 1
Organism Mycolicibacterium
RCSB PDB Entry 5o61
Reference Hentschel Jendrik, Burnside Chloe, Mignot Ingrid, Leibundgut Marc, Boehringer Daniel, Ban Nenad. 2017. The Complete Structure of the Mycobacterium smegmatis 70S Ribosome Cell Reports
Equivalence Class NR_all_76090.17, NR_all_89181.12, NR_all_92130.5
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound PHE
Residue . / 101
Chain MZ / BW
Non-redundant True
Interacting RNA chains DB/BW, B/A
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains B/A: rRNA, DB/BW: tRNA
RNA family global multiple
Volume 516.90 Å3
Hydrophobicity 0.569
Hydrophilicity 0.872
Buriedness 0.740
Don/acc character 2.121
SiteScore 1.203
D Score 1.090
Kd