Complex 7u2j
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.55 |
| System mass | 4564.91 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 7u2j |
| Reference | Syroegin Egor A, Aleksandrova Elena V, Polikanov Yury S. 2022. Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine Nucleic Acids Research |
| Equivalence Class |
NR_all_97519.80,
NR_all_89111.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | CLM |
| Residue | . / 4087 |
| Chain | ETA / 1A |
| Non-redundant | True |
| Interacting RNA chains | A/1A, BB/1w |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | A/1A: rRNA, BB/1w: tRNA |
| RNA family global | multiple |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | CLM |
| Residue | . / 103 |
| Chain | SBD / 2w |
| Non-redundant | True |
| Interacting RNA chains | FB/2A, GD/2w |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | FB/2A: rRNA, GD/2w: tRNA |
| RNA family global | multiple |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |