Complex 7s1g
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.48 |
| System mass | 2174.63 kDa |
| Deposition year | 2021 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Escherichia |
| RCSB PDB Entry | 7s1g |
| Reference | Tsai Kaitlyn, Stojković Vanja, Lee D. John, Young Iris D., Szal Teresa, Klepacki Dorota, Vázquez-Laslop Nora, Mankin Alexander S., Fraser James S., Fujimori Danica Galonić. 2022. Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_83717.187,
NR_all_19951.102
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | ZLD |
| Residue | . / 3111 |
| Chain | OI / I |
| Non-redundant | True |
| Interacting RNA chains | E/A, L/I |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | E/A: tRNA, L/I: rRNA |
| RNA family global | multiple |
| Volume | 615.00 Å3 |
| Hydrophobicity | 0.663 |
| Hydrophilicity | 1.062 |
| Buriedness | 0.776 |
| Don/acc character | 0.885 |
| SiteScore | 1.202 |
| D Score | 1.060 |
| Kd | — |