Complex 7lh5
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.27 |
| System mass | 4589.37 kDa |
| Deposition year | 2021 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 7lh5 |
| Reference | Golkar Tolou, Bassenden Angelia V., Maiti Krishnagopal, Arya Dev P., Schmeing T. Martin, Berghuis Albert M.. 2021. Structural basis for plazomicin antibiotic action and resistance Communications Biology |
| Equivalence Class |
NR_all_65795.87,
NR_all_97519.80
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | EDS |
| Residue | . / 1805 |
| Chain | KL / AA |
| Non-redundant | True |
| Interacting RNA chains | A/AA |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 194.82 Å3 |
| Hydrophobicity | 0.075 |
| Hydrophilicity | 0.911 |
| Buriedness | 0.571 |
| Don/acc character | 4.417 |
| SiteScore | 0.961 |
| D Score | 0.821 |
| Kd | — |
| Compound | EDS |
| Residue | . / 1787 |
| Chain | LNA / CA |
| Non-redundant | True |
| Interacting RNA chains | QC/DA, EC/CX, HB/CA |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | EC/CX: mRNA, HB/CA: rRNA, QC/DA: rRNA |
| RNA family global | multiple |
| Volume | 163.27 Å3 |
| Hydrophobicity | 0.084 |
| Hydrophilicity | 0.936 |
| Buriedness | 0.581 |
| Don/acc character | 3.516 |
| SiteScore | 0.862 |
| D Score | 0.688 |
| Kd | — |