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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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1215 RNA-SM complexes found
Structure of complex 9fib

9fib

Structure of 30S-IF1-IF3-mRNA-GE81112A complex

SM: A1IC4

Structure of complex 9fqz

9fqz

CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1

SM: 3HE ANM GDP HYG

Structure of complex 9g5d

9g5d

Assembly intermediate of human mitochondrial ribosome small subunit (State C)

SM: NAD

Structure of complex 9fra

9fra

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9frk

9frk

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9frl

9frl

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to SD mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fs6

9fs6

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9g6j

9g6j

The structure of the Candida albicans ribosome with tRNA-fMet, mRNA, and compounds (GEN and MFQ) with strong density for the P-site tRNA

SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET SPK YMZ

Structure of complex 9gha

9gha

Fusidic acid-locked Escherichia coli 70S ribosome with Staphylococcus aureus EF-G and a tRNA in pe/E chimeric state (CHI)

SM: FUA

Structure of complex 9fs8

9fs8

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aEF1A-like mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fsf

9fsf

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-MAP leaderless mRNA with h44 in up position

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9fxo

9fxo

CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA : LM32CS1C1 M2 OE MUTANT

SM: PAR PAR PAR PAR PAR PAR

Structure of complex 9fy0

9fy0

Cryo-EM structure of Saccharolobus solfataricus 30S initiation complex bound to Ss-aIF2beta leaderless mRNA

SM: SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9g06

9g06

Structure of 30S-IF1-IF3-mRNA-fMet-tRNA-GE81112A complex

SM: A1IC4

Structure of complex 9g1z

9g1z

Structure of Candida albicans 80S ribosome in complex with mefloquine (non-rotated state)

SM: SPK YMZ YMZ

Structure of complex 9gmo

9gmo

eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16

SM: EPE

Structure of complex 9gms

9gms

Mtb PNPase Rv2783c

SM: A1IM2 A1IM2 A1IM2

Structure of complex 9gmt

9gmt

Mtb PNPase Rv2783c Mutant L328F

SM: A1IM2 A1IM2 A1IM2

Structure of complex 9gr1

9gr1

E. coli 70S-TEC complex in delivery state

SM: PHE

Structure of complex 9gxx

9gxx

70S ribosome with doublet-decoding tRNASer3 bound to A-site GCA codon

SM: SPM

Structure of complex 9h0l

9h0l

70S ribosome with cognate tRNASer3 bound to A-site AGC codon

SM: SPM

Structure of complex 9h3g

9h3g

Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs and mRNA

SM: EPE TER

Structure of complex 9h51

9h51

Assembly intermediate of human mitochondrial ribosome small subunit in complex with PUS1, METTL15 and RBFA(IN conformation) (state M1)

SM: NAD SPM

Structure of complex 9h6i

9h6i

Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs, mRNA, and thermospermine

SM: EPE TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER

Structure of complex 9h8g

9h8g

Complex 5 30S-GE81112

SM: A1IC4

Structure of complex 9o3y

9o3y

Human 80S ribosome bound to IDB-002 stalled on FPAK-containing nascent chain

SM: A1B76

Structure of complex 9h90

9h90

Cryo-EM structure of the Vibrio natrigens 30S ribosomal subunit in complex with spectinomycin.

SM: SCM

Structure of complex 9h9h

9h9h

Complex 1 30S-IF1-IF2-IF3-GE81112

SM: A1IC4

Structure of complex 9h9j

9h9j

Complex 2 (BODY) 30S-IF1-IF3-tRNA-GE81112

SM: A1IC4

Structure of complex 9h9l

9h9l

Complex 3 (BODY) 30S-tRNA-GE81112

SM: A1IC4

Structure of complex 9h9n

9h9n

Complex 4 (BODY) 30S-GE81112 (weak residual tRNA)

SM: A1IC4

Structure of complex 9hcg

9hcg

Mouse mitoribosome large subunit assembly intermediate bound to NSUN4, METRF4, MRM2, GTPBP7 and MALSU1-L0R8F8-mt-ACP complex, State D (SAMC knock-out)

SM: SAH

Structure of complex 9hes

9hes

Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs, mRNA, and thermospermine

SM: EPE TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER TER

Structure of complex 9hl9

9hl9

CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH P/E-site tRNA AND mRNA : LM14Cs1H3 sKO STRAIN

SM: A1IWA

Structure of complex 9hmw

9hmw

Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs and mRNA

SM: EPE TER

Structure of complex 9i14

9i14

CRYO-EM STRUCTURE OF HCT15 POLYSOMES IN HYBRID-PRE STATE

SM: HYG

Structure of complex 9i1w

9i1w

High resolution structure of the thermophilic 60S ribosomal subunit of Chaetomium thermophilum

SM: SPM SPM

Structure of complex 9p8i

9p8i

In situ HHT and CHX treated human P-Z state 80S ribosome

SM: 3HE HMT SPM SPM SPM SPM SPM SPM SPM

Structure of complex 9i5t

9i5t

50S subunit of P. gingivalis ribosome with Lefamulin

SM: 62B

Structure of complex 9i88

9i88

Structure of the wild-type Staphylococcus aureus 70S ribosome complexed with clincelin

SM: A1I09

Structure of complex 9i89

9i89

Structure of the A2058-dimethylated Staphylococcus aureus 70S ribosome complexed with clincelin

SM: A1I09

Structure of complex 9imb

9imb

The crystal structure of human m5C methyltransferase NSUN6 bound to its S-adenosyl-L-methionine analog and a NECTIN-2 3'-UTR RNA substrate

SM: SFG SFG

Structure of complex 9j5p

9j5p

Crystal structure of B. subtilis CspR complexed with sinefungin and cellularly expressed tRNA Leu

SM: SFG

Structure of complex 9k0z

9k0z

EF-G2 bound 70S ribosome complex of M. smegmatis

SM: PHE

Structure of complex 9l5s

9l5s

Cryo-EM structure of the thermophile spliceosome (state B*Q1)

SM: M7M

Structure of complex 9l5t

9l5t

Cryo-EM structure of the thermophile spliceosome (state B*Q2)

SM: M7M

Structure of complex 9ljr

9ljr

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: CDP FAD

Structure of complex 9ljs

9ljs

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: CDP FAD

Structure of complex 9ljt

9ljt

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: CDP FAD

Structure of complex 9lju

9lju

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: FAD GDP

Structure of complex 9ljv

9ljv

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: C5P FAD

Structure of complex 9ljw

9ljw

Structural insights into the polymerase catalyzed FAD-capping of hepatitis C viral RNA

SM: GDP

Structure of complex 9mkk

9mkk

Structure of arbekacin bound Escherichia coli 70S ribosome

SM: 84G 84G

Structure of complex 9mnc

9mnc

Human 80S ribosome bound to small molecule SW393071

SM: A1BNL B3P

Structure of complex 9muj

9muj

RlmR 23S rRNA methyltransferase from Thermus thermophilus in complex with methylated rRNA (Um2552) and S-adenosyl-L-homocysteine (SAH)

SM: SAH

Structure of complex 9n2b

9n2b

Impacts of ribosomal RNA sequence variation on gene expression and phenotype: Cryo-EM structure of the rrsB ribosome (BBB-70S)

SM: ATP ATP

Structure of complex 9n2c

9n2c

Impacts of ribosomal RNA sequence variation on gene expression and phenotype: Cryo-EM structure of the rrsH ribosome (HBB-70S)

SM: ATP ATP

Structure of complex 9n5t

9n5t

Mycobacterium smegmatis 70S ribosome with small molecule drug MK-7762

SM: A1BWO

Structure of complex 9o2x

9o2x

Structure of WT E.coli ribosome 70S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site (S)-betahydroxyBocK charged NH-tRNAPyl

SM: PAR SPM

Structure of complex 9o2y

9o2y

Structure of WT E.coli ribosome 70S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site (R) beta-2-hydroxy-BocLysine acid charged NH-tRNAPyl

SM: PAR SPM