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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9i5t

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound 62B
Residue . / 2901
Chain IA / A
Non-redundant True
Interacting RNA chains J/A
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains J/A: rRNA
RNA family global rRNA
Volume 634.21 Å3
Hydrophobicity 0.307
Hydrophilicity 1.109
Buriedness 0.749
Don/acc character 1.682
SiteScore 1.184
D Score 1.028
Kd