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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9i14

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.34
System mass 3843.28 kDa
Deposition year 2025
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 9i14
Equivalence Class NR_all_46995.72, NR_all_50426.1
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound HYG
Residue . / 1901
Chain OK / S2
Non-redundant True
Interacting RNA chains E/A4, WA/S2
RNA environment detailled ion
RNA environment global RNA
RNA family chains E/A4: mRNA, WA/S2: rRNA
RNA family global multiple
Volume 391.36 Å3
Hydrophobicity 0.217
Hydrophilicity 1.260
Buriedness 0.679
Don/acc character 0.994
SiteScore 1.119
D Score 0.913
Kd