Harnessing RIBOnucleic acid - Small molecules Structures
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Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA
SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4
Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline
SM: 1PE 1PE PG4 PG4 PG4 PG4 PG4 T1C T1C
Structure of the Wild-type 70S E coli ribosome bound to Tigecycline
Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA
Structure of a 5-hydroxytryptophan aptamer
SM: 4PQ
RNA 15mer duplex binding with PZG monomer
SM: PZG PZG PZG PZG
Selective Small Molecule Inhibition of the FMN Riboswitch
SM: 6YG
Self-complimentary RNA 15mer binding with GMP monomers
SM: 5GP 5GP 5GP 5GP
Solution NMR structure of the GTP binding Class II RNA aptamer-ligand-complex containing a protonated adenine nucleotide with a highly shifted pKa.
SM: GTP
Crystal structure of Agelastatin A bound to the 80S ribosome
SM: 7MB 7MB
Crystal structure of geneticin (G418) bound to the yeast 80S ribosome
SM: GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET
Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking)
SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ
Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA
SM: 8UZ 8UZ 8UZ 8UZ
Crystal structure of Paromomycin bound to the yeast 80S ribosome
SM: PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR PAR
Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome
SM: 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ 8UZ
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02
SM: 95H EPE
The complete structure of the Mycobacterium smegmatis 70S ribosome
SM: PHE
iSpinach aptamer
SM: 1TU SPM
Crystal structure of Gentamicin bound to the yeast 80S ribosome
SM: LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL LLL
Crystal structure of haemanthamine bound to the 80S ribosome
SM: HN8 HN8
Structure of a guanidine-I riboswitch from S. acidophilus
SM: SPK
Methicillin sensitive Staphylococcus aureus 70S ribosome
SM: PAR
RNA primer-template complex with guanosine dinucleotide ligand G(5')pp(5')G
SM: 86S 86S
RNA primer-template complex with guanosine dinucleotide ligand G(5')ppp(5')G
SM: GP3 GP3
RNA primer-template complex with guanosine dinucleotide G(5')pppp(5')G ligand
SM: 86P 86P 86P 86P
RNA hairpin structure containing 2-MeImpG monomer analogue and 2-MeImp-oligomer analogue
SM: 8OS
70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II)
SM: FME
70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III)
70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc)
70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc)
RNA duplex with 2-MeImpG analogue bound-one binding site
SM: 8OS 8OS
RNA hairpin structure containing 2-MeImpG analogue bound
Structure of S-GNA dodecamer
SM: SPM
Co-crystal structure of the fluorogenic RNA Mango
SM: 74G 74G
Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog
SM: 917
Thermus thermophilus 70S ribosome lacking ribosomal protein uS17
SM: ARG ARG
RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue
Guanidine-II riboswitch P2 hairpin dimer from Pseudomonas aeruginosa
SM: SPM SPM SPM SPM SPM
Guanidine-II riboswitch P2 hairpin dimer with 5-bromoU substitution from Pseudomonas aeruginosa
SM: SPM SPM SPM SPM
Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
SM: M2D M2D
70S ribosome-EF-Tu H84A complex with GppNHp
SM: FME GNP PHE
70S ribosome-EF-Tu wt complex with GppNHp
70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA
SM: FME PHE
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3)
70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4)
SM: FME GTP PHE
Crystal structure of the Thermus thermophilus 70S ribosome in complex with methymycin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution
SM: MT9 MT9
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
SM: B6M
Structural Insight of Flavonoids binding to CAG repeat RNA that causes Huntington's Disease (HD) and Spinocerebellar Ataxia (SCAs)
SM: MYC MYC
Crystal structure of the Homo Sapiens cytoplasmic ribosomal decoding site in complex with G418
SM: GET GET GET GET
Crystal structure of the bacterial ribosomal decoding site in complex with 6'-fluoro sisomicin
SM: FSJ
Crystal structure of the protozoal cytoplasmic ribosomal decoding site in complex with 6'-fluoro sisomicin
Crystal structure of the Homo Sapiens cytoplasmic ribosomal decoding site in complex with G418 (P21212 form)
SM: GET
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site in complex with geneticin
SM: GET GET
Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site in complex with paromomycin
Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin
SM: PAR PAR PAR PAR PAR
Current selection range: to
Filter entries " Experimental resolution " between the two values. Global DB range: 0.6 – 11.2
Filter entries " Molecular weight (compound) " between the two values. Global DB range: 150 – 1000
Filter entries " Deposition date " between the two values. Global DB range: 1986 – 2027
Filter entries " Molecular weight (complex) " between the two values. Global DB range: 0 – 13090
Filter entries " Number of atoms " between the two values. Global DB range: 5 – 70
Filter entries " Number of interacting chains " between the two values. Global DB range: 1 – 4
Filter entries " Pocket size " between the two values. Global DB range: 15.9 – 394.0
Filter entries " SiteScore " between the two values. Global DB range: 0.3 – 1.3
Filter entries " Dscore " between the two values. Global DB range: -0.1 – 1.4
Filter entries " Exposure " between the two values. Global DB range: 0.1 – 1.0
Filter entries " Enclosure " between the two values. Global DB range: 0.3 – 1.0
Filter entries " Hydrophobicity " between the two values. Global DB range: 0.0 – 3.1
Filter entries " Hydrophilicity " between the two values. Global DB range: 0.2 – 2.8
Filter entries " Donor/Acceptor " between the two values. Global DB range: 0.0 – 5.0
Filter entries " Volume " between the two values. Global DB range: 21.2 – 1528.8
