Complex 5xi1
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Solution NMR |
| Experimental resolution | N/A |
| System mass | 6.41 kDa |
| Deposition year | 2017 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 5xi1 |
| Reference | Khan Eshan, Tawani Arpita, Mishra Subodh Kumar, Verma Arun Kumar, Upadhyay Arun, Kumar Mohit, Sandhir Rajat, Mishra Amit, Kumar Amit. 2018. Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington’s Disease (HD) and Spino Cerebellar Ataxia (SCAs) ACS Chemical Biology |
| Molecular Dynamics Simulation | mmb-A01WR, mmb-A01XI, mmb-A022A, mmb-A022T |
| Equivalence Class |
NR_all_83514.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | MYC |
| Residue | . / 101 |
| Chain | C / S |
| Non-redundant | False |
| Interacting RNA chains | B/A, A/S |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/S: unknown, B/A: unknown |
| RNA family global | unknown |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | MYC |
| Residue | . / 102 |
| Chain | D / S |
| Non-redundant | False |
| Interacting RNA chains | B/A, A/S |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/S: unknown, B/A: unknown |
| RNA family global | unknown |
| Volume | 90.21 Å3 |
| Hydrophobicity | 0.574 |
| Hydrophilicity | 0.684 |
| Buriedness | 0.571 |
| Don/acc character | 1.537 |
| SiteScore | 0.802 |
| D Score | 0.634 |
| Kd | — |