Complex 5v1l
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 1.20 |
| System mass | 16.13 kDa |
| Deposition year | 2017 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 5v1l |
| Reference | Schlegel Mark K., Foster Donald J., Kel’in Alexander V., Zlatev Ivan, Bisbe Anna, Jayaraman Muthusamy, Lackey Jeremy G., Rajeev Kallanthottathil G., Charissé Klaus, Harp Joel, Pallan Pradeep S., Maier Martin A., Egli Martin, Manoharan Muthiah. 2017. Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA Journal of the American Chemical Society |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | SPM |
| Residue | . / 303 |
| Chain | H / B |
| Non-redundant | True |
| Interacting RNA chains | A/A, B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: synthetic construct, B/B: synthetic construct |
| RNA family global | synthetic construct |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |