Harnessing RIBOnucleic acid - Small molecules Structures
Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-C)
SM: GCP
Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with iboxamycin, mRNA, deacylated A- and E-site tRNAphe, and aminoacylated P-site fMet-tRNAmet at 2.55A resolution
SM: 6IF
40S ribosomal subunit of the 80S Giardia intestinalis assemblage A ribosome with Emetine bound in V1 conformation
SM: YAT
40S ribosomal subunit of the 80S Giardia intestinalis assemblage A ribosome with Emetine bound in V2 conformation with mRNA and three tRNAs.
Cryo-EM consensus structure of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand
SM: PRF
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)
SM: 3H3 ANM
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
SM: 3H3 ANM GSP
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
SM: 3HE GSP HMT
Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
SM: PAR
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site meta-aminobenzoic acid charged NH-tRNAPhe
SM: SPM
Cryo-EM structure of 3DVA component 0 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand
Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to the near-cognate AUG codon (Structure II)
Structure of the Escherichia coli 70S ribosome in complex with A-site tRNAIle(LAU) bound to the cognate AUA codon (Structure III)
Cryo-EM structure of 3DVA component 1 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand
DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase
SM: DGT
Bombyx mori R2 retrotransposon initiating target-primed reverse transcription
SM: TTP
mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)
Structure of the Cas7-11-Csx29-guide RNA-target RNA (non-matching PFS) complex
SM: C5P
SARS-CoV-2 E-RTC complex with RNA-nsp9 and GMPPNP
SM: GNP
Crystal structure of NAD+ -II riboswitch in complex with NAD+
SM: NAD
Crystal structure of NAD+ -II riboswitch in complex with NMN
SM: NMN
Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
SM: CTP
Cryo-EM structure of the the NS5-NS3 RNA-elongation complex
SM: CDP
Crystal structure of MnmM from B. subtilis complexed with Gln-TTG anti-codon stem loop and SAM (2.90 A)
SM: SAM
Crystal structure of MnmM from S. aureus complexed with SAM and tRNA anti-codon stem loop (ASL) (1.55 A)
Crystal structure of NAD-II riboswitch (two strands) with NMN
Crystal structure of NAD-II riboswitch (two strands) with NR
SM: NNR
Crystal structure of NAD-II riboswitch (single strand) with NMN
Crystal structure of NAD-II riboswitch (single strand) with NAD
SM: NAD NMN
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
A new fluorescent RNA aptamer bound with N618
SM: O2I
A new fluorescent RNA aptamer bound with N
SM: NI4
A new fluorescent RNA aptamer bound with N565
SM: NJL
A new fluorescent RNA aptamer bound with N571
SM: O00
A new fluorescent RNA aptamer bound with N, iridium hexammine soak
A new fluorescent RNA aptamer_III bound with N
A new fluorescent RNA aptamer bound with N, manganese soak
Crystal structure of NAD-II riboswitch (two strands) with NMN at 1.67 angstrom
Interaction between a fluoroquinolone derivative KG022 and RNAs: effect of base pairs 3' adjacent to the bulge out residues
SM: 53D
The Tet-S1 state of G264A mutated Tetrahymena group I intron with 6nt 3'/5'-exon and 2-aminopurine nucleoside
SM: OJI
Dibekacin-bound E.coli 70S ribosome in the PURE system
SM: 84D SPM
Arbekacin-bound E.coli 70S ribosome in the PURE system
SM: 84G SPM
Dibekacin-added human 80S ribosome
SM: 84D
Arbekacin-added human 80S ribosome
SM: 84G
Wheat 80S ribosome stalled on AUG-Stop boron dependently with cycloheximide
SM: 3HE
Wheat 80S ribosome pausing on AUG-Stop with cycloheximide
Crystal structure of RhoBAST complexed with TMR-DN
SM: V8C
Cryo-EM structure of the human 55S mitoribosome with Tigecycline
SM: T1C
Cryo-EM structure of the human 39S mitoribosome with Tigecycline
Cryo-EM structure of the human 80S ribosome with Tigecycline
Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A
SM: GDP T1C
Crystal structure of Broccoli aptamer with DFHBI-1T
SM: 2ZY
Cryo-EM structure of the yeast 80S ribosome with tigecycline, Not5 and P-site tRNA
Crystal structure of Red Broccoli aptamer with OBI
SM: A1EBI
Crystal structure of 2'-dG-III riboswitch with 2'-dG
SM: GNG
Current selection range: to