Complex 8g5y
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.29 |
| System mass | 3894.94 kDa |
| Deposition year | 2023 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 8g5y |
| Reference | Holm Mikael, Natchiar S. Kundhavai, Rundlet Emily J., Myasnikov Alexander G., Watson Zoe L., Altman Roger B., Wang Hao-Yuan, Taunton Jack, Blanchard Scott C.. 2023. mRNA decoding in human is kinetically and structurally distinct from bacteria Nature |
| Equivalence Class |
NR_all_65061.63
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 3H3 |
| Residue | . / 5523 |
| Chain | AJ / L5 |
| Non-redundant | True |
| Interacting RNA chains | C/L5 |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | C/L5: rRNA |
| RNA family global | rRNA |
| Volume | 310.07 Å3 |
| Hydrophobicity | 0.353 |
| Hydrophilicity | 0.940 |
| Buriedness | 0.644 |
| Don/acc character | 1.095 |
| SiteScore | 0.954 |
| D Score | 0.982 |
| Kd | — |
| Compound | ANM |
| Residue | . / 5501 |
| Chain | EI / L5 |
| Non-redundant | True |
| Interacting RNA chains | C/L5 |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | C/L5: rRNA |
| RNA family global | rRNA |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |