Complex 8gs2
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.84 |
| System mass | 316.39 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Desulfonema |
| RCSB PDB Entry | 8gs2 |
| Reference | Kato Kazuki, Okazaki Sae, Schmitt-Ulms Cian, Jiang Kaiyi, Zhou Wenyuan, Ishikawa Junichiro, Isayama Yukari, Adachi Shungo, Nishizawa Tomohiro, Makarova Kira S., Koonin Eugene V., Abudayyeh Omar O., Gootenberg Jonathan S., Nishimasu Hiroshi. 2022. RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease Science |
| Equivalence Class |
NR_all_56375.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | C5P |
| Residue | . / 101 |
| Chain | E / D |
| Non-redundant | True |
| Interacting RNA chains | B/D |
| RNA environment detailled | protein, other |
| RNA environment global | RNA/Other |
| RNA family chains | B/D: unknown |
| RNA family global | unknown |
| Volume | 707.95 Å3 |
| Hydrophobicity | 0.242 |
| Hydrophilicity | 1.334 |
| Buriedness | 0.821 |
| Don/acc character | 0.555 |
| SiteScore | 1.082 |
| D Score | 0.998 |
| Kd | — |