HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8fc6

System information

Experimental technique X-ray
Experimental resolution 2.35
System mass 4428.57 kDa
Deposition year 2022
Molecule type RNA/Protein
# RNA entities 1
Organism Thermus
RCSB PDB Entry 8fc6
Reference Chen Chih-Wei, Leimer Nadja, Syroegin Egor A., Dunand Clémence, Bulman Zackery P., Lewis Kim, Polikanov Yury S., Svetlov Maxim S.. . Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A Nature Communications

Compound ARG
Residue . / 231
Chain ORA / 1B
Non-redundant True
Interacting RNA chains B/1B
Volume 192.77 Å3
Hydrophobicity 0.000
Hydrophilicity 1.991
Buriedness 0.596
Don/acc character 0.986
SiteScore 1.032
D Score 0.585

Compound ARG
Residue . / 320
Chain GTA / 1F
Non-redundant True
Interacting RNA chains A/1A
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -

Compound HGR
Residue . / 4020
Chain HQA / 1A
Non-redundant True
Interacting RNA chains A/1A
Volume 428.41 Å3
Hydrophobicity 0.854
Hydrophilicity 1.094
Buriedness 0.779
Don/acc character 0.688
SiteScore 1.204
D Score 1.050

Compound HGR
Residue . / 3743
Chain KLC / 2A
Non-redundant True
Interacting RNA chains BB/2A
Volume 691.83 Å3
Hydrophobicity 0.341
Hydrophilicity 1.640
Buriedness 0.718
Don/acc character 0.566
SiteScore 1.163
D Score 0.836

Compound TEL
Residue . / 4021
Chain IQA / 1A
Non-redundant True
Interacting RNA chains A/1A
Volume 119.36 Å3
Hydrophobicity 0.163
Hydrophilicity 1.153
Buriedness 0.597
Don/acc character 0.429
SiteScore 0.702
D Score 0.626

Compound TEL
Residue . / 3744
Chain LLC / 2A
Non-redundant True
Interacting RNA chains BB/2A
Volume 103.59 Å3
Hydrophobicity 0.024
Hydrophilicity 2.084
Buriedness 0.592
Don/acc character 0.127
SiteScore 0.801
D Score 0.451