HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8fc2

System information

Experimental technique X-ray
Experimental resolution 2.50
System mass 4428.47 kDa
Deposition year 2022
Molecule type RNA/Protein
# RNA entities 1
Organism Thermus
RCSB PDB Entry 8fc2
Reference Chen Chih-Wei, Leimer Nadja, Syroegin Egor A., Dunand Clémence, Bulman Zackery P., Lewis Kim, Polikanov Yury S., Svetlov Maxim S.. . Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A Nature Communications

Compound ARG
Residue . / 230
Chain PRA / 1B
Non-redundant True
Interacting RNA chains B/1B
Volume 117.31 Å3
Hydrophobicity 0.000
Hydrophilicity 2.107
Buriedness 0.647
Don/acc character 1.128
SiteScore 0.885
D Score 0.346

Compound ARG
Residue . / 318
Chain LTA / 1F
Non-redundant True
Interacting RNA chains A/1A
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -

Compound HGR
Residue . / 4022
Chain JQA / 1A
Non-redundant True
Interacting RNA chains A/1A
Volume 498.04 Å3
Hydrophobicity 1.023
Hydrophilicity 0.933
Buriedness 0.800
Don/acc character 0.747
SiteScore 1.239
D Score 1.116

Compound HGR
Residue . / 3730
Chain BLC / 2A
Non-redundant True
Interacting RNA chains BB/2A
Volume 728.53 Å3
Hydrophobicity 0.632
Hydrophilicity 1.321
Buriedness 0.750
Don/acc character 0.846
SiteScore 1.185
D Score 0.960

Compound ZIT
Residue . / 4023
Chain KQA / 1A
Non-redundant True
Interacting RNA chains A/1A
Volume 580.01 Å3
Hydrophobicity 0.141
Hydrophilicity 1.906
Buriedness 0.757
Don/acc character 0.544
SiteScore 1.190
D Score 0.773

Compound ZIT
Residue . / 3731
Chain CLC / 2A
Non-redundant True
Interacting RNA chains BB/2A
Volume 492.89 Å3
Hydrophobicity 0.666
Hydrophilicity 1.185
Buriedness 0.743
Don/acc character 0.765
SiteScore 1.180
D Score 0.999