HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8fc1

System information

Experimental technique X-ray
Experimental resolution 2.50
System mass 4428.66 kDa
Deposition year 2022
Molecule type RNA/Protein
# RNA entities 1
Organism Thermus
RCSB PDB Entry 8fc1
Reference Chen Chih-Wei, Leimer Nadja, Syroegin Egor A., Dunand Clémence, Bulman Zackery P., Lewis Kim, Polikanov Yury S., Svetlov Maxim S.. . Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A Nature Communications

Compound ARG
Residue . / 230
Chain ISA / 1B
Non-redundant True
Interacting RNA chains B/1B
Volume 190.37 Å3
Hydrophobicity 0.017
Hydrophilicity 2.117
Buriedness 0.620
Don/acc character 0.931
SiteScore 1.049
D Score 0.559

Compound ARG
Residue . / 319
Chain BUA / 1F
Non-redundant True
Interacting RNA chains A/1A
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -

Compound ERY
Residue . / 4042
Chain DRA / 1A
Non-redundant True
Interacting RNA chains A/1A
Volume 466.14 Å3
Hydrophobicity 0.202
Hydrophilicity 1.755
Buriedness 0.748
Don/acc character 0.399
SiteScore 1.183
D Score 0.817

Compound ERY
Residue . / 3732
Chain RLC / 2A
Non-redundant True
Interacting RNA chains BB/2A
Volume 573.50 Å3
Hydrophobicity 0.646
Hydrophilicity 1.261
Buriedness 0.749
Don/acc character 0.890
SiteScore 1.184
D Score 0.978

Compound HGR
Residue . / 4041
Chain CRA / 1A
Non-redundant True
Interacting RNA chains A/1A
Volume 792.67 Å3
Hydrophobicity 0.484
Hydrophilicity 1.650
Buriedness 0.744
Don/acc character 0.567
SiteScore 1.181
D Score 0.848

Compound HGR
Residue . / 3731
Chain QLC / 2A
Non-redundant True
Interacting RNA chains BB/2A
Volume 590.99 Å3
Hydrophobicity 0.973
Hydrophilicity 0.989
Buriedness 0.801
Don/acc character 1.036
SiteScore 1.229
D Score 1.098